The rapid development of high-throughput technologies has opened up a new “omics” era providing an unprecedented opportunity for scientists and clinicians to gain deeper insights into molecular mechanisms, even at single cell resolution. The analysis and integration of the data arising from these methodological approaches is revolutionizing daily clinical practice, moving the precision medicine paradigm forward. In this scenario, the identification of tissue and circulating molecular biomarkers with high sensitivity and specificity to be employed for diagnosis, prognosis, and treatment prediction will undoubtedly benefit patients, but only few have been successfully implemented into the clinic.

This Special Issue of BioTech includes research articles, short reports, and reviews focused on the employment of “omics” (e.g., genomics, epigenomics, transcriptomics, proteomics, metabolomics, lipidomics, microbiomics) technologies for biomarker development both at translational and clinical level.

Dr. Alfonso Urbanucci
Dr. Simona Tavolari
Guest Editors

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• gene signatures
• oncology
• free circulating DNA
• next-generation sequencing
• molecular biomarkers