Special Issue "Innovation in Bone Metastasis"

A special issue of Cancers (ISSN 2072-6694).

Deadline for manuscript submissions: 31 August 2022.

Special Issue Editors

Prof. Dr. Vincenzo Denaro
E-Mail Website
Guest Editor
Department of Orthopaedic and Trauma Surgery, Campus Bio-medico University, Via Álvaro del Portillo, 200, 00128 Rome, Italy
Interests: spine surgery; bone pathology; replacement; orthopaedic surgery
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Special Issue Information

Dear Colleagues, 

Bone is the third most frequent site of metastases. In particular, about 70% of breast cancer patients and 60% of prostate cancer patients develop diffuse bone metastases in the late stages of the disease. Bone metastases are a serious challenge for the surgeon and the patient, leading in most cases to drug-resistant pain, pathological fractures, and, in late stages, to death. Therefore, bone metastases may require either preventive (impending fracture) or curative (pathologic fracture) bone fixation. Today, most treatments for bone metastases are palliative, and surgery remains the gold standard. The surgery of bone metastases frequently requires the replacement of the affected bone segment with a biocompatible implant. These implants can be made of synthetic materials or harvested from cadavers and adapted to the patient’s anatomy through various surgical techniques. In recent years, thanks to the advent of 3D printing and the development of new biomaterials, it has become possible to improve these patients’ outcomes by creating custom-made prostheses, making surgery easier and more effective.

This Special Issue focuses on innovations in the field of bone metastases. The development of new biomaterials, new prostheses, and technologies for bone metastasis surgery is essential to improve the overall survival and quality of life of these patients. Basic, translational, and clinical research in this field holds promise to improve the quality of life and survival rates of patients with bone metastasis.

Prof. Dr. Umile Giuseppe Longo
Prof. Dr. Vincenzo Denaro
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers

This special issue is now open for submission.
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