Molecular Mechanism of the Interaction Between Cells and Extracellular Matrix in Cancer Progression
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Molecular Cancer Biology".
Deadline for manuscript submissions: closed (30 September 2022) | Viewed by 18717
Special Issue Editors
Interests: breast cancer; extracellular matrix; cell adhesion and migration; metastasis
Special Issue Information
Dear Colleagues,
During solid tumor progression, aberrant changes in extracellular matrix (ECM) composition and organization diversify the three-dimensional spatial topography of biochemical and biophysical properties that impact cellular behavior. To survive and disseminate, cancer cells rely on their ability to sense changes in the microenvironment and respond by dynamically remodeling the surrounding ECM.
This Special Issue of Cancers will focus on how the dynamic reciprocity between cells and their microenvironment, that is, the interactions between tumor, stromal cells, and the ECM, impacts tumor progression. We welcome research papers as well as expert reviews that are focused on, but are not limited to, the study of the molecular mechanisms underlying the dynamic reciprocity involved in: a) generating hospitable microenvironments within the primary tumor or metastatic niche; b) priming tumor cells for dormancy or metastatic growth; c) developing drug resistance.
Dr. Suzanne Ponik
Dr. Seiichiro Ishihara
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cancer progression
- extracellular matrix
- mechano-signaling
- matrix remodeling
- metastatic niche
- dormancy
- metastasis
- drug resistance