The Role of Adipocyte Crosstalk in the Tumor Microenvironment
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Tumor Microenvironment".
Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 3676
Special Issue Editors
Interests: adipocyte; cancer; pancreas; obesity; adiponectin; leptin; SHP-2; adipokine; microenvironment; MAPK
Special Issue Information
Dear Colleagues,
We are assembling a special issue in the journal Cancers to focus on highlighting work related to pathways associated with the adipose tissue and its crosstalk in the tumor microenvironment. Tumor initiation and progression are influenced by multiple factors related to systemic and intercellular communication from other tissues. For instance, adipocytes within the adipose tissue can affect tumor intercellular communications and contribute to signaling changes that impact the behavior of various tumor types. In particular, adipocytes are capable of influencing multiple hallmarks of cancer cells like proliferation, invasion, cell death, angiogenesis, metabolism, and immunity. A wide field of expertise will be required to build a comprehensive analysis of adipose tissue-tumor crosstalk. The purpose of this special issue it to highlight advances in the understanding of molecular mechanisms that mediate adipose-tumor interactions and to uncover novel pathways that will benefit and advance the field of obesity-associated tumors. Additionally, adipose-stromal interactions with fibroblasts, immune cells, and endothelial cells will also be covered in the context of the tumor microenvironment. We anticipate this issue will expand our understanding of adipose tissue communication and further the development of effective therapeutics to subvert pro-tumorigenic mediators.
Dr. Michael VanSaun
Dr. Zobeida Cruz-Monserrate
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- adipocyte
- adipose
- tumor microenvironment
- crosstalk
- stroma
- lipid
- adipokine
- fatty acid
- cachexia
- wasting
- obesity
- cancer
