Whole Breast Radiotherapy versus Endocrine Therapy in Early Breast Cancer
A special issue of Cancers (ISSN 2072-6694).
Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 7101
Special Issue Editors
Interests: cancer research; mediator response; chemotherapy; radiation therapy
Special Issues, Collections and Topics in MDPI journals
Interests: breast cancer; stereotactic radiotherapy; intraoperative radiotherapy; radiotherapy for pediatric patients; radiotherapy for elderly patients
Special Issues, Collections and Topics in MDPI journals
Interests: breast cancer; radiotherapy; deep inspiration breath hold
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Multiple randomized trials have established adjuvant endocrine therapy and whole breast irradiation as the standard approach after breast conserving surgery in early stage breast cancer. The omission of whole breast radiotherapy has likewise been studied in multiple trials, resulting in reduced local control with maintained survival rates, and has, therefore, been adapted as a treatment option in selected patients in several guidelines. Omitting endocrine therapy instead of whole breast irradiation might also be a valuable option as both treatments have distinctly different side effect profiles. However, the clinical outcomes of breast conserving surgery and endocrine therapy versus breast conserving surgery and whole breast irradiation have not been thoroughly analyzed. In this Special Issue, we want to discuss this question.
Prof. Edwin Bölke
Dr. Christiane Matuschek
Dr. Stefanie Corradini
Dr. David Krug
Guest Editors
Manuscript Submission Information
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Keywords
- randomized trials
- meta-analysis
- endocrine therapy
- radiation
- trials