Phase Separation, Chromatin Organization and Transcription for Cancers
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Molecular Cancer Biology".
Deadline for manuscript submissions: closed (1 September 2022) | Viewed by 18237
Special Issue Editors
Interests: cancer; epigenetics; transcription; gene regulation; myogenesis; differentiation
Special Issue Information
Dear Colleagues,
Our genome is organized in the nucleus where DNA is wrapped around histone proteins to form chromatin. Any access to the DNA requires factors that help in chromatin reorganization, such as decompaction and compaction of the chromatin. Many factors influence the maintenance and regulation of these higher-order structures, also known as chromatin domains. Among these, epigenetic regulators play a vital role in remodeling the chromatin landscape to maintain transcriptionally active and repressed domains. In this issue, we will showcase recent discoveries in the field that have identified phase-separation and chromatin domains to be dysregulated in cancers and their influence on gene expression.
Prof. Dr. Reshma Taneja
Dr. Sudhakar Jha
Guest Editors
Manuscript Submission Information
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Keywords
- transcription
- chromatin
- gene regulation
- histones
- cancer
- epigenetics