Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Resistance of Hematological Malignancies to CAR T Cell Therapy
edited by
submission deadline 28 Mar 2024 | Viewed by 89 | Submission Open
Keywords: NHL; ALL; CAR T cell; immunotherapy; resistance; apoptosis
Advances in Zebrafish Cardiac Disease Models
edited by
submission deadline 30 Mar 2024 | 2 articles | Viewed by 3211 | Submission Open
Keywords: zebrafish; heart; cardiomyocytes; heart disease; cardiac hypertrophy; regenerative medicine; cardiac regeneration; translational models
(This special issue belongs to the Section Cells of the Cardiovascular System)
Male Infertility Update: Current Knowledge on Etiology, Comorbidities, Diagnosis and Treatment submission deadline 30 Mar 2024 | 1 articles | Viewed by 1155 | Submission Open
Keywords: male infertility; diagnosis; treatment; etiology; pre-testicular/testicular/post-testicular causes; genetic causes; seminal parameters; hormonal parameters; ultrasound; general health; azoospermia
Cancer-Associated Fibroblasts: Challenges and Directions submission deadline 30 Mar 2024 | Viewed by 231 | Submission Open
Keywords: cancer-associated fibroblast (CAFs); tumor microenvironment (TME); fibroblast activation protein alpha (FAPα ); immunotherapy; cytokines; angiogenesis; metastasis; FAP inhibitors; radioligands; imaging agents
New Insights into Tyrosine Kinase Alterations in Human Diseases submission deadline 31 Mar 2024 | 3 articles | Viewed by 7889 | Submission Open
Keywords: mechanism of tyrosine kinase activation/inactivation in human diseases; mutations of tyrosine kinases in cancer; tyrosine kinases as therapeutic targets; novel therapeutic approaches to target tyrosine kinases
(This special issue belongs to the Section Cell Signaling)
Feature Papers in "Stem Cells" 2023 submission deadline 31 Mar 2024 | 3 articles | Viewed by 7229 | Submission Open
(This special issue belongs to the Section Stem Cells)
Genetics and Pathomechanisms of Amyotrophic Lateral Sclerosis (ALS)
edited by
submission deadline 31 Mar 2024 | 3 articles | Viewed by 5006 | Submission Open
Keywords: genetics of ALS/FTD; ER stress and UPR; mitochondria and mitochondrial-associated membranes; Ca2+ signaling; excitotoxicity/neuronal networks; synaptic dysfunction; therapeutic strategies
(This special issue belongs to the Section Cellular Pathology)
DNA Replication and Genetic Research: An Honorary Issue in Memory of Prof. James L. German submission deadline 31 Mar 2024 | 4 articles | Viewed by 4143 | Submission Open
Keywords: DNA replication; genomic instability; BLM; Bloom syndrome; DNA damage; helicases: hereditary cancer predisposition syndromes; premature aging syndromes; DNA repair; RecQ; genetic disease; chromosome stability
(This special issue belongs to the Section Cell and Gene Therapy)
Properties and Function of Enzymes in the Metabolic Regulation of Oxidative and Reductive Processes
edited by
submission deadline 31 Mar 2024 | 3 articles | Viewed by 3769 | Submission Open
Keywords: oxidoreductases; dehydrogenases; pyridine redox cofactors; flavine redox cofactors; oxygenases; hydroxylases; peroxidases; oxidative stress; antioxidant enzymes; glutathione; metallothionein
(This special issue belongs to the Section Cell Microenvironment)
Novel Microenvironment-Based Immune Changes Revealed by RNA Sequencing in Cancer or Metabolic Diseases submission deadline 31 Mar 2024 | 2 articles | Viewed by 3676 | Submission Open
Keywords: immune changes; RNA sequencing; microenvironment; CITE-seq; ATAC-seq; molecular changes; function changes; metabolic diseases; cancer
(This special issue belongs to the Section Cellular Immunology)
Cilia-Mediated Signaling Pathways submission deadline 31 Mar 2024 | 3 articles | Viewed by 3545 | Submission Open
Keywords: primary cilia; motile cilia; ciliary signaling; ciliopathy; development; cellular homeostasis; unicellular organism; invertebrate and vertebrate models; cell/tissue culture
(This special issue belongs to the Section Cell Signaling)
Pathogenesis of Prion Diseases
edited by Ilia V. Baskakov
submission deadline 31 Mar 2024 | 3 articles | Viewed by 3422 | Submission Open
Keywords: prions; prion diseases; Creutzfeldt– Jakob disease; neurodegenerative diseases; prion strains; species barrier; neuroinflammation; reactive microglia; reactive astrocytes; glycosylation
(This special issue belongs to the Section Cellular Pathology)
Natural Killer Cells in Cancer Immunotherapy
edited by
submission deadline 31 Mar 2024 | 2 articles | Viewed by 2904 | Submission Open
(This special issue belongs to the Section Cellular Immunology)
Molecular Studies of Drosophila Signaling Pathways
edited by
submission deadline 31 Mar 2024 | 4 articles | Viewed by 2641 | Submission Open
Keywords: regulation of signaling pathways; signal transduction mechanisms; signal dynamics; signaling networks and cross-talk; pathways and disease; cell-fate choices; developmental pattering; transcriptional regulation; computational modeling
Exploring the Regulation Mechanism of Cardiomyocyte Proliferation and Cardiac Regeneration
edited by and
submission deadline 31 Mar 2024 | 1 articles | Viewed by 2521 | Submission Open
Keywords: cardiovascular disease; cardiomyocyte proliferation and cardiac regeneration; underlying mechanism; disease model; compensate for lost myocardial cells; repair damaged heart tissue; improve cardiac functions
Role of Microenvironment in the Control of Cell Proliferation, Death, and Autophagy submission deadline 31 Mar 2024 | 2 articles | Viewed by 2508 | Submission Open
(This special issue belongs to the Section Cell Microenvironment)
A Vertebrate Model for Human Molecular Genetics submission deadline 31 Mar 2024 | 2 articles | Viewed by 2238 | Submission Open
Keywords: molecular genetics; exome; developmental and functional biology; vertebrate model; zebrafish; in vivo; functional characterization
Oral Microbiome in Oral and Systemic Disease: Association or Causation?
edited by
submission deadline 31 Mar 2024 | 2 articles | Viewed by 2173 | Submission Open
Keywords: oral microbiome; oral diseases; oral– systemic link
(This special issue belongs to the Section Cellular Pathology)
Microenvironmental Factors and Functional Modulation in Mesenchymal Stem Cells 2.0 submission deadline 31 Mar 2024 | 2 articles | Viewed by 1961 | Submission Open
Keywords: mesenchymal stem cells; inflammation; microenvironment; regeneration of mesenchymal stem cell receptors; stem cell differentiation
(This special issue belongs to the Section Stem Cells)
Cellular and Molecular Mechanisms of Lysosomal Storage Disorders
edited by
submission deadline 31 Mar 2024 | 1 articles | Viewed by 1921 | Submission Open
Keywords: lysosomes; lysosomal storage disorders; enzyme replacement; gene therapy; substrate reduction; pharmacological chaperones; autophagy; endosomal dysfunction
(This special issue belongs to the Section Cellular Pathology)
Signaling Pathways Responsible for Breast Cancer Metastasis
edited by
submission deadline 31 Mar 2024 | 1 articles | Viewed by 1862 | Submission Open
Keywords: EMT; immune suppression; organ tropism; CTC; secreted DNAs; secreted RNAs
(This special issue belongs to the Section Cell Signaling)
Molecular Nutrition: How Nutrients and Nutraceuticals Could Impact on Aging and Longevity
edited by and
submission deadline 31 Mar 2024 | 1 articles | Viewed by 1769 | Submission Open
Keywords: nutrition; nutraceutical; aging; longevity; molecular nutrition; signalling pathway
(This special issue belongs to the Section Cellular Aging)
Antioxidants in Redox Homeostasis of Plant Development submission deadline 31 Mar 2024 | 1 articles | Viewed by 1677 | Submission Open
Keywords: reactive oxygen species; radical scavenging; oxidative stress; plant growth and development; primary and secondary metabolites
(This special issue belongs to the Section Plant, Algae and Fungi Cell Biology)
The Cell Biology of Fertilization submission deadline 31 Mar 2024 | 1 articles | Viewed by 1317 | Submission Open
Keywords: oocyte maturation; acrosome reaction; gamete interaction; actin remodelling; calcium; monospermy
(This special issue belongs to the Section Cell Proliferation and Division)
Neuromodulation and Biomarkers in Neurodegenerative Diseases submission deadline 31 Mar 2024 | 1 articles | Viewed by 1035 | Submission Open
Cellular and Molecular Dysregulations of Solid Tumors
edited by
submission deadline 31 Mar 2024 | Viewed by 401 | Submission Open
Keywords: solid tumors; signaling pathways; genetic dysregulations; cellular abnormalities; cancer treatment
Novel Advances in Cellular and Molecular Mechanisms Governing Liver Pathophysiology
edited by
submission deadline 31 Mar 2024 | Viewed by 292 | Submission Open
Keywords: functional genomics; transcriptional regulation; cell identity; cell plasticity; single-cell omics; cellular dialogues; hepatocytes; non-parenchymal cells; liver pathophysiology
(This special issue belongs to the Section Cellular Pathology)
Novel Insights into the Mechanisms of Vascular Injury and Repair submission deadline 31 Mar 2024 | Viewed by 266 | Submission Open
Keywords: endothelium; immune modulation; progenitor cell contribution; signalling; cell-to-cell communication
Advancements in Cancer Immunotherapy beyond Checkpoint Blockade
edited by and
submission deadline 31 Mar 2024 | Viewed by 239 | Submission Open
Keywords: T-cell function in cancer; immune checkpoint blockade; CD8+ T cell responses; myeloid cells; immunotherapy targets; cancer progression
(This special issue belongs to the Section Cellular Immunology)
Brain Injury in Patients with Cardiac and Pulmonary Diseases submission deadline 31 Mar 2024 | Viewed by 213 | Submission Open
Keywords: brain– lung crosstalk; brain– heart crosstalk; cerebrovascular complications; mechanical circulatory support devices; respiratory complications; brain injury; acute respiratory distress syndrome; COVID-19
Engineering Stem Cells for Islet Replacement Therapy
edited by Nidheesh Dadheech and
submission deadline 31 Mar 2024 | Viewed by 196 | Submission Open
Keywords: beta cell replacement therapy; stem cells; pluripotent stem cells; diabetes; biomanufacturing; biomaterials and encapsulation; gene editing; islet transplantation; immunomodulation strategies
(This special issue belongs to the Section Stem Cells)
Advances in the Research of Cardiovascular Genetics submission deadline 31 Mar 2024 | Viewed by 191 | Submission Open
Keywords: genetics; epigenetics; next-generation sequencing; genome editing; gene therapy; disease modeling; cell therapy
Bone Regeneration and Repair: Replacing What Has Been Lost through Science
edited by Paolo Savadori
submission deadline 31 Mar 2024 | Viewed by 125 | Submission Open
Keywords: bone; regenerative; bone defect; tissue engineering; histology; animal models; bone biology; 3D printing; biomaterials; bone surgery
Neuropathic Pain: From Mechanism to Therapy
edited by
submission deadline 31 Mar 2024 | Viewed by 121 | Submission Open
microRNA as Biomarker II
edited by and
submission deadline 10 Apr 2024 | 4 articles | Viewed by 8107 | Submission Open
Keywords: disease biomarker; circulating miRNA; saliva miRNA; urine miRNA; blood miRNA; neurodegenerative disease; cancer biomarker; health check; diagnose; cardiovascular disorders; diabetes aheade sick; exosome miRNA; aberrant miRNA expression
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Hemoglobin and Other Globin Types: Structure, Function and Evolution
edited by and
submission deadline 10 Apr 2024 | 2 articles | Viewed by 1745 | Submission Open
Keywords: hemoglobin; myoglobin; cytoglobin; neuroglobin; androglobin; globin-coupled sensor; truncated globin; flavohemoglobin; oxygen
(This special issue belongs to the Section Cellular Biophysics)
RNA in Focus
edited by
submission deadline 10 Apr 2024 | 2 articles | Viewed by 1414 | Submission Open
Keywords: RNA localization; mRNA translation and regulation; RNA modification; non-coding RNAs; RNA therapeutics; RNA nanotechnology
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Cell Death Mechanisms and Therapeutic Opportunities in Glioblastoma
edited by
submission deadline 15 Apr 2024 | 13 articles | Viewed by 22584 | Submission Open
Keywords: apoptosis; autophagy; cell death mechanisms; cell signaling; glioblastoma; therapeutic opportunities
(This special issue belongs to the Section Cells of the Nervous System)
Exclusive Review Papers in "Cellular Immunology"
edited by
submission deadline 15 Apr 2024 | 4 articles | Viewed by 12096 | Submission Open
Keywords: immunology; autoimmunity; oncology; transplantation; lymphocytes; dendritic cells; monocytes; plasma cells
(This special issue belongs to the Section Cellular Immunology)
Focus on Machinery of Cell Death
edited by , Prashanta Kumar Panda and
submission deadline 15 Apr 2024 | 2 articles | Viewed by 4633 | Submission Open
Keywords: cell death; autophagy; apoptosis; necrosis; ferroptosis; metabolism; stem cell biology; infection; aging; development; Alzheimer’ s; neurodegeneration; therapy
(This special issue belongs to the Section Cellular Pathology)
The Role of Cellular Senescence in Health, Disease, and Aging
edited by
submission deadline 15 Apr 2024 | 2 articles | Viewed by 2511 | Submission Open
Keywords: apoptosis; cancer; cell cycle; DNA damage; metabolic diseases; oxidative stress; senolysis; senescence; therapeutic approach
Molecular and Cellular Mechanisms Underlying Meiotic Divisions submission deadline 15 Apr 2024 | 1 articles | Viewed by 1215 | Submission Open
Keywords: meiotic division; meiotic spindle; meiotic maturation; oocyte; oogenesis; spermatozoid; spermatogenesis; gamete; egg; fertilization; mating; oocyte to embryo transition; haploidy; aneuploidy; cell division control; cell division checkpoints; chromatin remodeling; regulation of protein translation; regulation of maternal mRNAs; model organisms
(This special issue belongs to the Section Reproductive Cells and Development)
Modern Translational Approaches in NeuroHIV and HIV Comorbidities Research
edited by Olimpia Meucci and Zachary A. Klase
submission deadline 15 Apr 2024 | Viewed by 129 | Submission Open
Keywords: neuroHIV; HAND; cognitive impairment; neuroinflammation; neural circuits; brain vasculature; learning and memory; CNS therapeutics; HIV models; antiretrovirals; substance use; opioid; cancer; brain bioenergetics; lipids; neurons; glia; cell-to-cell communication
Critical Targets and Therapeutic Strategies of Breast Cancer submission deadline 15 Apr 2024 | Viewed by 78 | Submission Open
Keywords: biomarkers; microenvironment; subtypes; dormancy; therapy; resistance
Cell Asymmetry and Polarity: Guiding Cellular Behavior and Development
edited by
submission deadline 19 Apr 2024 | Viewed by 179 | Submission Open
Keywords: cell asymmetry; cell polarity; tissue morphogenesis; planar cell polarity (PCP) pathway; wnt pathway; therapeutic implications
(This special issue belongs to the Section Cell Signaling)
The Role of the Obesity Paradox in Cancer Progression and Immunotherapy
edited by
submission deadline 20 Apr 2024 | 2 articles | Viewed by 3489 | Submission Open
Keywords: obesity paradox; tumor immunology; tumor metastasis; immunotherapy
(This special issue belongs to the Section Cell Microenvironment)
Advances in the Biogenesis, Biology, and Functions of Noncoding RNAs
edited by Xinguo Chen
submission deadline 20 Apr 2024 | 1 articles | Viewed by 795 | Submission Open
Keywords: noncoding RNA biogenesis; long noncoding RNA (lncRNAs); circular RNA (circRNAs); enhancer RNA (eRNAs); microRNA (miRNAs); PIWI-interacting RNAs (pi-RNAs); tRNA-derived fragments (tRFs)
Molecular Mechanism of Rectal Insulin Signalling in Inflammatory Bowel Disease
edited by
submission deadline 20 Apr 2024 | Viewed by 72 | Submission Open
Keywords: inflammatory bowel disease; insulin receptor; enteroendocrine cells; rectal insulin treatment; inflammation; microbiota; differentiation; local administration
Molecular Mechanism of Protein Synthesis in Alzheimer's Disease
edited by Antonella Borreca
submission deadline 25 Apr 2024 | Viewed by 141 | Submission Open
Keywords: protein synthesis; UPR system; ER stress; translational factor and cognition; Alzheimer’ s disease; translational control; post-translational modification
(This special issue belongs to the Section Cells of the Nervous System)
Islet Transplantation
edited by Shinichi Matsumoto
submission deadline 26 Apr 2024 | 6 articles | Viewed by 5942 | Submission Open
Keywords: allogeneic islet transplantation; islet isolation; immunosuppression for islet transplantation; autologous islet transplantation; xenogeneic islet transplantation; transplantation site for islet transplantation; regenerative medicine for the treatment of diabetes
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