Autophagy and Chronic Non Communicable Degenerative Diseases
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Autophagy".
Deadline for manuscript submissions: closed (15 June 2021) | Viewed by 529
Special Issue Editors
Interests: prostate cancer; proline-rich tyrosine kinase 2; cell metabolism; autophagy; resilience wellbeing and health status
Interests: adaptive immunity; T lymphocytes; inflammation
Interests: endoplasmic reticulum (ER) stress response; analysis of the dynamics of transport in the early secretory pathway; mechanisms regulating autophagosome biogenesis; role of autophagy in neurodegenerative and infectious diseases; role of autophagy in cell growth control and unconventional secretion; pharmacological modulation of autophagy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Autophagy is a major cellular homeostatic system, which acts as a pro-survival mechanism under conditions of stress, maintaining cellular integrity by regenerating metabolic precursors and clearing subcellular debris.
The repertoire of routine housekeeping functions exerted by autophagy includes the elimination of defective proteins and damaged organelles, the prevention of abnormal protein aggregates accumulation, which are linked to neurodegenerative diseases and other clinically relevant conditions, as well as the removal of intracellular pathogens.
In view of the key role of such functions in maintaining basal, cellular and tissue homeostasis, as well as developmental regulation in higher organisms, dysregulation of autophagy has been widely implicated in several pathophysiological processes, including cancer, metabolic and neurodegenerative disorders, cardiovascular and immune-mediated diseases and aging.
The aim of this special issue is to collect the current knowledge on autophagy and chronic non communicable degenerative diseases, so that this issue will become a” brain storming gym” where diverse or even opposite points of view could be presented and debated, providing the scientific community with a broader view of the multiple roles played by such a fundamental cellular process. To this aim, we will welcome and take in consideration both review and original research articles on this specific topic.
Prof. Donatella Tramontano
Dr. Claudio Procaccini
Dr. Maurizio Renna
Guest Editors
Manuscript Submission Information
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Keywords
- autophagy
- apoptosis
- protein and cellular homeostasis
- cell and immune metabolism
- signalling pathways
- inflammatory and autoimmune disorders
- neurodegenerative diseases
- Cardiovascular diseases
