Latest Advances in Nanobiosensors: Novel Materials and Applications

A special issue of Chemosensors (ISSN 2227-9040). This special issue belongs to the section "Applied Chemical Sensors".

Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 6032

Special Issue Editors

Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology, 08028 Barcelona, Spain
Interests: nanoplasmonics; optical sensor; nanomaterials for sensing; lab-on-a-chip; organ-on-chip; biosensors
Special Issues, Collections and Topics in MDPI journals
1. Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology, Baldiri I Reixac, 10-12, 08003 Barcelona, Spain
2. ICREA-Institució Catalana de Recerca i Estudis Avançats, 08010 Barcelona, Spain
Interests: biosensors; electrochemistry; nanotechnology; flow techniques; peptides and proteins; enzymatic reactions; total synthesis; biomaterials; cell culture; tissue culture
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

According to the latest market reports, the biosensor market is expected to be worth USD 31.5 billion by 2024. Point-of-care still represents the leading segment in the overall biosensor market (about 57%); however, several food toxicity applications, bioreactors, environmental protection, and others have emerged during the last few years. Among different transduction methods, electrochemical biosensors are still the largest market due to their widespread quantification and analysis in biochemical and biological processes. However, optical biosensors are expected to achieve the fastest growth in the coming years. This rise in the use of optical biosensors is mainly related to their universal analytical coverage: optical biosensors are applicable for structural studies, fermentation monitoring, receptor–cell interactions, concentration, kinetic, and equilibrium analysis, among other applications.

Moreover, the development of biosensors based on nanostructured materials has been the focus of extensive research and development, since the integration of nanomaterials into biosensors, generally, leads to improved sensitivity, multiplexed, and real-time detection capabilities. This Special Issue focuses on the advancement and development of biosensors based on nanostructured materials contributing to innovative biosensing platforms. The applications portfolio includes clinical diagnostics, veterinary diagnostics, environmental monitoring, food analysis, and other biochemical and biological analysis.

Dr. Gerardo Arturo López Muñoz
Prof. Dr. Javier Ramón Azcón
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Chemosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Nanostructured materials
  • Nanoporous materials
  • Metamaterials
  • Photonic and plasmonic nanocrystals
  • Electrochemical biosensors
  • Optical biosensors
  • Nanomechanical biosensors
  • Piezoelectric biosensors
  • Nanoplasmonic biosensors
  • Surface-enhanced Raman spectroscopy biosensors
  • Nano-interferometer and nano-resonator based biosensors
  • Nanoparticle-based biosensors
  • Lateral flow biosensors
  • Fluorescence-based biosensor
  • Multiplexed/multi-analyte detection
  • Lab-on-a-chip
  • Point-of-care
  • Organ-on-chip
  • Organoids
  • Environmental monitoring
  • Food analysis
  • Gas analysis
  • Healthcare
  • Tissue engineering

Published Papers (2 papers)

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Research

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15 pages, 3763 KiB  
Article
Development of a Tri-Functional Nanoprobe for Background-Free SERS Detection of Sialic Acid on the Cell Surface
by Septila Renata, Nitish Verma, Zhijay Tu, Rong-Long Pan, Mario Hofmann and Chun-Hung Lin
Chemosensors 2021, 9(5), 92; https://0-doi-org.brum.beds.ac.uk/10.3390/chemosensors9050092 - 26 Apr 2021
Cited by 2 | Viewed by 2892
Abstract
Sialic acid (SA) on the surface of cells is indispensable in numerous physiological and pathological processes, and sensitive and reproducible detection of SA is crucial for diagnosis and therapy in many diseases. Here, we developed a tri-functional nanoprobe as a sensitive and straightforward [...] Read more.
Sialic acid (SA) on the surface of cells is indispensable in numerous physiological and pathological processes, and sensitive and reproducible detection of SA is crucial for diagnosis and therapy in many diseases. Here, we developed a tri-functional nanoprobe as a sensitive and straightforward surface-enhanced Raman spectroscopy (SERS) nanoprobe for sialoglycan detection on cell surfaces. The reporter was designed to provide three key functionalities that make it ideal for SA detection. First, we employed two recognition groups, phenylboronic acid and an ammonium group, that enhance SA recognition and capture efficiency. Second, we used cyano as the Raman reporter because it emits in the cellular Raman silent region. Finally, thiol acted as an anchoring agent to conjugate the reporter to silver nanocubes to provide SERS enhancement. Our molecular nanoprobe design demonstrated the ability to detect SA on the cell surface with high sensitivity and spatial resolution, opening up new routes to cellular diagnostics. Full article
(This article belongs to the Special Issue Latest Advances in Nanobiosensors: Novel Materials and Applications)
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Review

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30 pages, 11484 KiB  
Review
Triboelectric Nanogenerators in Sustainable Chemical Sensors
by Qiliang Zhu, Xia Cao and Ning Wang
Chemosensors 2022, 10(11), 484; https://0-doi-org.brum.beds.ac.uk/10.3390/chemosensors10110484 - 15 Nov 2022
Cited by 8 | Viewed by 2356
Abstract
The rapid development of sensing technology has created an urgent need for chemical sensor systems that can be rationally integrated into efficient, sustainable, and wearable electronic systems. In this case, the triboelectric nanogenerator (TENG) is expected to be a major impetus to such [...] Read more.
The rapid development of sensing technology has created an urgent need for chemical sensor systems that can be rationally integrated into efficient, sustainable, and wearable electronic systems. In this case, the triboelectric nanogenerator (TENG) is expected to be a major impetus to such innovation because it can not only power the sensor by scavenging mechanical energies and transforming them into electricity but also act as the chemical sensor itself due to its intrinsic sensitivity towards the chemical reaction that occurs at the triboelectric interface. In this review, recent research achievements of chemical sensors that are based on TENGs are comprehensively reviewed according to the role of TENGs in the system, that is, pure power supplies or self-powered active chemical sensors. Focus is put on discussing the design criteria and practical applications of the TENG-based active sensors in different fields, which is unfolded with a classification that includes biosensors, gas sensors, and ion sensors. The materials selection, working mechanism, and design strategies of TENG-based active chemical sensor systems (CSSs) are also discussed, ending with a concise illustration of the key challenges and possible corresponding solutions. We hope this review will bring inspiration for the creation and development of TENG-based chemical sensors with higher sensitivity, simpler structure, and enhanced reliability. Full article
(This article belongs to the Special Issue Latest Advances in Nanobiosensors: Novel Materials and Applications)
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