Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
2.0
2.4
Journals
Children
Special Issues
Type 1 Diabetes in Children: Clinical Advances and Future Challenges
share announcement

Type 1 Diabetes in Children: Clinical Advances and Future Challenges

A special issue of Children (ISSN 2227-9067).

Deadline for manuscript submissions: closed (30 November 2021) | Viewed by 5621

Special Issue Editor

Dr. Peter Simm

E-Mail Website
Guest Editor
Department of Endocrinology and Diabetes, Royal Children's Hospital Melbourne, Parkville, VIC 3052, Australia
Interests: paediatric endocrinology; growth; type 1 diabetes; bone health; rickets

Special Issue Information

Dear Colleagues,

The management of type 1 diabetes mellitus is rapidly changing and is now almost unrecognizable since insulin was first discovered in 1922. With advances in screening, diagnosis, immunotherapies, insulin types, and diabetes-related technology, it is an exciting and ever-changing field. Young people and their families have more tools than ever at their disposal in order to optimize management, yet many challenges remain. Technological advances often result in a greater intensity of day-to-day input for the patient and can be frustrating if there are issues such as sensor dropout, inaccuracies, recurrent alarms. or insulin pump line failure. Access to these technologies is not always equitably distributed, with many countries facing issues with even basic supplies, such as insulin. Young people are experiencing greater stress and anxiety than ever before, and dealing with the burden of a chronic disease can make these underlying issues much more pronounced. Ultimately, a cure that means that endogenous insulin production is restored is the key focus of biological advances. In recent years, immunotherapy has been shown to delay the progression of islet cell destruction in early trials, but much work needs to be done before this can be used widely in clinical practice. In this Special Issue, we wish to explore the current status of diabetes care across a number of areas, from technology to adjustment.

Dr. Peter Simm
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Type 1 diabetes
  • Continuous glucose monitoring
  • Immunotherapy
  • Quality of life
  • Screening
  • Diabetes technology

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

9 pages, 456 KiB  
Article
The Impact of Insulin-Induced Lipodystrophy on Glycemic Variability in Pediatric Patients with Type 1 Diabetes
by Fortunato Lombardo, Bruno Bombaci, Angela Alibrandi, Giulia Visalli, Giuseppina Salzano and Stefano Passanisi
Children 2022, 9(7), 1087; https://0-doi-org.brum.beds.ac.uk/10.3390/children9071087 - 20 Jul 2022
Cited by 7 | Viewed by 2811
Abstract
Lipodystrophy is the most common dermatological complication in patients with diabetes on insulin therapy. Despite the high frequency of lipodystrophy, there are still several difficulties in giving advice about avoidance into practice among children and adolescents with type 1 diabetes and their caregivers. [...] Read more.
Lipodystrophy is the most common dermatological complication in patients with diabetes on insulin therapy. Despite the high frequency of lipodystrophy, there are still several difficulties in giving advice about avoidance into practice among children and adolescents with type 1 diabetes and their caregivers. This cross-sectional study aims to evaluate the prevalence of insulin-induced lipodystrophy in a cohort of pediatric patients with type 1 diabetes, to identify associated clinical factors and to assess its influence on glycemic control. Two hundred and twelve patients attending our Diabetes Center during a three-month period were enrolled. The presence of lipodystrophy was assessed by inspection and palpation procedures. Demographic and clinical data including type of treatment, frequency of rotation of insulin administration sites, and glucose metrics of the previous 30 days were assessed and statistically analyzed. Prevalence of lipohypertrophy was 44.3%. Two patients were affected by lipoatrophy (0.9%). Improper rotation of insulin administration sites and low awareness on lipodystrophy were associated to the occurrence of this skin condition (p = 0.050 and p = 0.005, respectively). When comparing patients with and without lipodystrophy, a significant difference in glycemic variability parameters was detected (p = 0.036 for coefficient of variation, p = 0.029 for standard deviation score of glucose levels). Lipodystrophy still represents a common complication in patients on insulin therapy. The present study reveals its negative impact on glycemic variability. This finding emphasizes the importance of prevention strategies to minimize the occurrence of this dermatological complication that may interfere with clinical history of the disease. Full article
(This article belongs to the Special Issue Type 1 Diabetes in Children: Clinical Advances and Future Challenges)
►▼ Show Figures

Figure 1

8 pages, 262 KiB  
Article
Attitudes and Perceptions of School Teachers in Melilla Regarding the Care Provided to Students with Type 1 Diabetes
by Trinidad Luque-Vara, Elisabet Fernández-Gómez, Marta Linares-Manrique, Silvia Navarro-Prado, María Angustias Sánchez-Ojeda and Carmen Enrique-Mirón
Children 2021, 8(12), 1137; https://0-doi-org.brum.beds.ac.uk/10.3390/children8121137 - 05 Dec 2021
Cited by 2 | Viewed by 2035
Abstract
The main objective of the study was to assess the perception of non-university teachers in the city of Melilla to help students with type 1 diabetes mellitus (T1DM), as well as their attitudes towards helping these students in diabetic emergencies. This observational, descriptive, [...] Read more.
The main objective of the study was to assess the perception of non-university teachers in the city of Melilla to help students with type 1 diabetes mellitus (T1DM), as well as their attitudes towards helping these students in diabetic emergencies. This observational, descriptive, cross-sectional study analyzed the answers given by 441 teachers from 25 public institutions in the city of Melilla to a survey on the attitude and perception regarding the capacity of educational institutions (16 questions) to help and manage students with T1DM. Out of 47.6% of teachers who represent having had students with TIDM, only 4.8% acknowledged having been trained in diabetes. The percentage that has experienced a hypoglycaemia episode at the institution was 29.9%. More than half of participants acknowledged that their educational institution is not prepared to manage diabetic emergencies. Only 5.7% stated their institutions have glucagon in their first-aid kit and less than half of participants (44.7%) would be willing to administer it if necessary. Teachers of educational institutions believe they have not been particularly trained in the care of students living with T1DM and point out that their educational institutions are not prepared to help in diabetic emergencies. Full article
(This article belongs to the Special Issue Type 1 Diabetes in Children: Clinical Advances and Future Challenges)
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop