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Crystals
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Biomaterials Surface Integrity
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Biomaterials Surface Integrity

A special issue of Crystals (ISSN 2073-4352). This special issue belongs to the section "Biomolecular Crystals".

Deadline for manuscript submissions: closed (31 December 2021) | Viewed by 11936

Special Issue Editors

Dr. Nicolas Lebon

E-Mail Website
Guest Editor
1. Unité de Recherche Biomatériaux Innovants et Interfaces, URB2I, UR 4462, Université Sorbonne Paris Nord, F-93000 Bobigny, France
2. Faculté de Chirurgie Dentaire, Université de Paris, F-92120 Montrouge, France
Interests: surface integrity; roughness; milling; dental biomaterials; CAD/CAM
Dr. Laurent Tapie

E-Mail Website
Guest Editor
Senior Lecturer, Université Sorbonne Paris Nord, Unité de Recherche Biomatériaux Innovants et Interfaces, URB2I, UR 4462, F-93000, Bobigny, France, Université de Paris, F-92120 Montrouge, France
Interests: dental biomaterials; bio-inspired materials; CAD/CAM; machining; additive manufacturing
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Nowadays prostheses intended for biomedical use are manufactured by various processes such as machining, 3D printing, molding, forging, etc.  All these manufacturing processes generate a characteristic “imprint” on the prosthesis shape called surface integrity. The concept of surface integrity represents a new and preferential approach to characterize the biomaterials surface and sub-surface properties regard to the functional requirement of prosthesis. Surface integrity analysis provides a comprehensive evaluation of the surface and its impact on the performance of the prosthesis. The concept of surface integrity is made up several components such as roughness, dislocations, porosity, electrical conductivity, wettability, etc. However, the integrity of the surface obtained, which must be suitable to meet expected clinical requirements (mechanical properties, optical properties, thermal properties, electrical properties, chemical properties, etc.) is influenced by the manufacturing process parameters used. To assess surface integrity, a lot of characterization techniques are available depending on the observation scales including, but not limited to spectroscopy, optical imaging methods, nanoindentation, magnetic property measurements, roughness measurements, and X-Ray inspection. Surface integrity is a fundamental concept in engineering and gives an invaluable source of information about the surface characsteritics and its ability to meet the clinical functional specifications.

Dr. Nicolas Lebon
Dr. Laurent Tapie
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Crystals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Prosthesis
  • Implantable medical device
  • Surface engineering
  • Surface integrity
  • Surface properties and function
  • Clinical and biological surface requirements
  • Biomaterial surface
  • Surface processes
  • Surface characterization techniques
  • Surface metrology

Published Papers (6 papers)

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Editorial

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2 pages, 160 KiB  
Editorial
Biomaterials Surface Integrity
by Nicolas Lebon and Laurent Tapie
Crystals 2022, 12(4), 438; https://0-doi-org.brum.beds.ac.uk/10.3390/cryst12040438 - 22 Mar 2022
Viewed by 1105
Abstract
Nowadays, prostheses or implantable medical devices intended for biomedical use are manufactured using various processes, such as machining, 3D printing, molding, and forging [...] Full article
(This article belongs to the Special Issue Biomaterials Surface Integrity)

Research

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10 pages, 1810 KiB  
Article
Obtaining Biocompatible Porous Composite Material Based on Zinc-Modified Hydroxyapatite and Lactide-Glycolide Copolymer
by Daria Lytkina, Anastasiya Gutsalova, Dmitry Fedorishin and Irina Kurzina
Crystals 2021, 11(12), 1519; https://0-doi-org.brum.beds.ac.uk/10.3390/cryst11121519 - 05 Dec 2021
Cited by 1 | Viewed by 1689
Abstract
The development of surgery in the field of bone tissue reconstruction provides a stable demand for new materials for implants. Of particular interest are materials based on hydroxyapatite, which are close in chemical composition to the elemental composition and structure of bone and [...] Read more.
The development of surgery in the field of bone tissue reconstruction provides a stable demand for new materials for implants. Of particular interest are materials based on hydroxyapatite, which are close in chemical composition to the elemental composition and structure of bone and have similar biologically active properties. In this work, the regularities of the formation of new composite materials based on a zinc-modified hydroxyapatite framework coated with a copolymer of lactide and glycolide were revealed for the first time. The aim of this work was to obtain porous composite materials based on zinc-modified hydroxyapatite and a copolymer of lactide and glycolide with properties suitable for use as a material for bone implants. The phase and elemental composition of the composites was studied by infrared spectroscopy, X-ray diffraction, and X-ray spectral microanalysis. Regularities have been established between the surface properties and the composition of materials, as well as their biocompatibility, determined using monocytes isolated from human peripheral blood. The antibacterial activity of the materials against gram-positive and gram-negative bacteria was determined. Full article
(This article belongs to the Special Issue Biomaterials Surface Integrity)
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12 pages, 3607 KiB  
Article
The Effect of Threads Geometry on Insertion Torque (IT) and Periotest Implant Primary Stability: A High-Density Polyurethane Simulation for the Anterior Mandible
by Stefano Fanali, Margherita Tumedei, Pamela Pignatelli, Morena Petrini, Adriano Piattelli and Giovanna Iezzi
Crystals 2021, 11(3), 308; https://0-doi-org.brum.beds.ac.uk/10.3390/cryst11030308 - 20 Mar 2021
Cited by 6 | Viewed by 2936
Abstract
The implant geometry provides a key role in the osseointegration process and is able to improve the mechanical interaction and primary stability into the bone tissue. The aim of the present investigation was to compare different implant profiles to evaluate their influence on [...] Read more.
The implant geometry provides a key role in the osseointegration process and is able to improve the mechanical interaction and primary stability into the bone tissue. The aim of the present investigation was to compare different implant profiles to evaluate their influence on the primary stability on high-density polyurethane block. Methods: A total of 100 implants were used on 20 pcf polyurethane density in the present investigation, i.e., 20 implants for each of 5 groups (A, B, C, D, and E), characterized by different thread pitch and geometry. The insertion torque (IT), and Periotest mean values were recorded during the implant positioning. Results: Mean values for insertion torque values were higher for the group C and group E implant profiles when compared to all other groups (p < 0.01). No significant differences were detected between these two groups (p < 0.05). Lower IT (<20 Ncm2) were presented by groups A, B, and D (p < 0.05). All groups showed negative Periotest values. Group C implants showed the lowest level of Periotest values (p < 0.05). No significant Periotest differences were found between group B and group D and between group A and group E (p > 0.05). Conclusions: Implants with a wider and V-thread profile and a round apex showed a higher stability in a standardized polyurethane foam. Their use could be suggested in high-density bone in clinical practice. Full article
(This article belongs to the Special Issue Biomaterials Surface Integrity)
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Review

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14 pages, 2300 KiB  
Review
Milled Surface Integrity: Application to Fixed Dental Prosthesis
by Nicolas Lebon and Laurent Tapie
Crystals 2021, 11(5), 559; https://0-doi-org.brum.beds.ac.uk/10.3390/cryst11050559 - 18 May 2021
Cited by 1 | Viewed by 2059
Abstract
Surface integrity is a multiphysics (biological, mechanical, optical, chemical, esthetic, etc.) and multiscale (from nm to mm) concept. It is defined as the residual signature left on the surface by the manufacturing or post-treatment process and permits correlating the process with the expected [...] Read more.
Surface integrity is a multiphysics (biological, mechanical, optical, chemical, esthetic, etc.) and multiscale (from nm to mm) concept. It is defined as the residual signature left on the surface by the manufacturing or post-treatment process and permits correlating the process with the expected surface functionalities. Thanks to the advances made in mechanical engineering, the concept of surface integrity has been transposed to dentistry and oral science. The surface integrity concept transposed to fixed dental prostheses is presented in this article. The main components of surface integrity and their correlations within the triptych of surface integrity–process–clinical functionalities are presented. Full article
(This article belongs to the Special Issue Biomaterials Surface Integrity)
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Other

1 pages, 467 KiB  
Correction
Correction: Crenn et al. Influence of Anodized Titanium Surfaces on the Behavior of Gingival Cells in Contact with: A Systematic Review of In Vitro Studies. Crystals 2021, 11, 1566
by Marie-Joséphine Crenn, Pierre Dubot, Elie Mimran, Olivier Fromentin, Nicolas Lebon and Patrice Peyre
Crystals 2022, 12(7), 893; https://0-doi-org.brum.beds.ac.uk/10.3390/cryst12070893 - 24 Jun 2022
Viewed by 711
Abstract
In the original article [...] Full article
(This article belongs to the Special Issue Biomaterials Surface Integrity)
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23 pages, 2067 KiB  
Systematic Review
Influence of Anodized Titanium Surfaces on the Behavior of Gingival Cells in Contact with: A Systematic Review of In Vitro Studies
by Marie-Joséphine Crenn, Pierre Dubot, Elie Mimran, Olivier Fromentin, Nicolas Lebon and Patrice Peyre
Crystals 2021, 11(12), 1566; https://0-doi-org.brum.beds.ac.uk/10.3390/cryst11121566 - 15 Dec 2021
Cited by 5 | Viewed by 2433 | Correction
Abstract
Electrochemically anodized (EA) surfaces promise enhanced biological properties and may be a solution to ensure a seal between peri-implant soft tissues and dental transmucosal components. However, the interaction between the modified nano-structured surface and the gingival cells needs further investigation. The aim of [...] Read more.
Electrochemically anodized (EA) surfaces promise enhanced biological properties and may be a solution to ensure a seal between peri-implant soft tissues and dental transmucosal components. However, the interaction between the modified nano-structured surface and the gingival cells needs further investigation. The aim of this systematic review is to analyze the biological response of gingival cells to EA titanium surfaces in in vitro studies with a score-based reliability assessment. A protocol aimed at answering the following focused question was developed: “How does the surface integrity (e.g., topography and chemistry) of EA titanium influence gingival cell response in in vitro studies?”. A search in three computer databases was performed using keywords. A quality assessment of the studies selected was performed using the SciRAP method. A total of 14 articles were selected from the 216 eligible papers. The mean reporting and the mean methodologic quality SciRAP scores were 87.7 ± 7.7/100 and 77.8 ± 7.8/100, respectively. Within the limitation of this review based on in vitro studies, it can be safely speculated that EA surfaces with optimal chemical and morphological characteristics enhance gingival fibroblast response compared to conventional titanium surfaces. When EA is combined with functionalization, it also positively influences gingival epithelial cell behavior. Full article
(This article belongs to the Special Issue Biomaterials Surface Integrity)
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