Biomaterials Characterization for Medical Applications

A special issue of Crystals (ISSN 2073-4352). This special issue belongs to the section "Biomolecular Crystals".

Deadline for manuscript submissions: closed (20 February 2021) | Viewed by 4785

Special Issue Editors

Special Issue Information

Dear Colleagues,

Biomedical applications of metallic alloys offer new perspectives and opportunities for materials scientists. The aim of this Special Issue is to publish high-impact papers presenting new research in the field of biodegradable materials and metallic biomaterials. At present, more and more obtaining procedures and technologies are available next to advanced characterization techniques.

The title of the Special Issue covers a wide range of topics: characterization of different types of biomaterials, from obtaining to in vivo analysis highlighting their structure, properties, and functions. In this Special Issue of Crystals, we will gather the top research results from researchers in various fields related to obtaining, processing, and utilizing biomaterials from different chemical elements. Topics of interest include biodegradable and biocompatible alloys (Mg-based alloys, Zn-based alloys, Ti-based alloys, Co-Cr alloys, etc.), modern processing technologies, in vitro and in vivo biological responses, and characterization techniques. For this purpose, original research articles, review articles, and significant preliminary communications are invited, with particular interest in articles describing current research trends and future perspectives in biomaterials characterization used in medical applications.

This Special Issue on “Biomaterials Characterization for Medical Applications” aims to publish some of the best research and reviews performed in the area of metallic biomaterials applications and will cover several topics, such as:

  • Biodegradable metallic biomaterials
  • New metallic alloys as biomaterials
  • Osseointegration
  • Metal/tissue interfaces
  • Biomechanical design and characterization
  • Biofunctionalization
  • Corrosion-resistant biomaterials
  • Additive manufacturing of metallic biomaterials
  • Design of metallic implants and prosthesis
  • Biomaterials for tissue engineering and regenerative medicine
  • Microporous, mesoporous, and nanoporous biomaterials
Dr. Bogdan Istrate
Prof. Dr. Munteanu Corneliu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Crystals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (2 papers)

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Research

11 pages, 2359 KiB  
Article
Fabrication, Characterization and In Vitro Cytotoxicity of Mesoporous β-Tricalcium Phosphate Using the Spray Drying Method
by Henni Setia Ningsih, Leonhard Tannesia, Hsiang-Ho Chen and Shao-Ju Shih
Crystals 2021, 11(3), 252; https://0-doi-org.brum.beds.ac.uk/10.3390/cryst11030252 - 02 Mar 2021
Cited by 3 | Viewed by 2182
Abstract
Mesoporous beta tricalcium phosphate (β-TCP) has recently attracted significant interest as an artificial bone tissue in orthopedics. However, a scalable process is required to meet future demands. Spray drying is one of the potential synthesis methods owing to its low cost and scalable [...] Read more.
Mesoporous beta tricalcium phosphate (β-TCP) has recently attracted significant interest as an artificial bone tissue in orthopedics. However, a scalable process is required to meet future demands. Spray drying is one of the potential synthesis methods owing to its low cost and scalable production. In this study, various mesoporous β-TCP powders were calcined in the range of 800 to 1100 °C, with particle sizes ranging from ~0.3 to ~1.8 μm, specific surface areas from ~16 to ~64 m2/g, and average pore sizes of 3 nm. Except for the 800 °C calcined powder, the other β-TCP powders (calcination temperatures of 900, 1000, and 1100 °C) exhibited no cytotoxicity. These results indicate that spray-dried mesoporous β-TCP powders were obtained. Finally, the corresponding formation mechanisms are discussed. Full article
(This article belongs to the Special Issue Biomaterials Characterization for Medical Applications)
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11 pages, 6209 KiB  
Article
Long Term Evaluation of Biodegradation and Biocompatibility In-Vivo the Mg-0.5Ca-xZr Alloys in Rats
by Eusebiu-Viorel Sindilar, Corneliu Munteanu, Sorin Aurelian Pasca, Iuliana Mihai, Madalina Elena Henea and Bogdan Istrate
Crystals 2021, 11(1), 54; https://0-doi-org.brum.beds.ac.uk/10.3390/cryst11010054 - 11 Jan 2021
Cited by 5 | Viewed by 2014
Abstract
Biodegradable alloys in Mg have the advantages of traditional metallic materials and those of biodegradable polymers with superior strength, lower density and ideal rigidity for fixing bone fractures. The biocompatibility and biodegradability of the five concentrations of Mg-0.5Ca-xZr alloys used were assessed using [...] Read more.
Biodegradable alloys in Mg have the advantages of traditional metallic materials and those of biodegradable polymers with superior strength, lower density and ideal rigidity for fixing bone fractures. The biocompatibility and biodegradability of the five concentrations of Mg-0.5Ca-xZr alloys used were assessed using clinical and laboratory examinations that followed over time: tissue reaction, histological and imaging (RX, CT and SEM) evolution at 1, 2, 4 and 8 weeks after implant. The main purpose of this study was to investigate in vivo the long-term effect of Mg-0.5Ca-xZr alloys in rats. The results confirmed that Mg-0.5Ca-xZr alloys are biocompatible and biodegradable and are recommended to be used as possible materials for new orthopedics devices. Full article
(This article belongs to the Special Issue Biomaterials Characterization for Medical Applications)
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