Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
4.0
2.6
Journals
Dentistry Journal
Special Issues
Research in Oral Health and Systemic Health: A Themed Issue...
share announcement

Research in Oral Health and Systemic Health: A Themed Issue Honoring Professor Jukka H. Meurman

A special issue of Dentistry Journal (ISSN 2304-6767). This special issue belongs to the section "Oral Hygiene, Periodontology and Peri-implant Diseases".

Deadline for manuscript submissions: closed (30 June 2022) | Viewed by 19045

Special Issue Editors

Prof. Dr. Jukka H. Meurman

E-Mail Website
Honoring Guest Editor
Department of Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, PB 63 (Biomedicum, Haartmaninkatu 8), 00014 Helsinki, Finland
Interests: oral infection; systemic health; probiotics; candida, saliva, periodontal disease
Prof. Dr. Yrsa Le Bell

E-Mail Website
Guest Editor
Institute of Dentistry, University of Turku, Turku, Finland
Interests: oral rehabilitation; temporomandibular disorders; oral and facial pain
Prof. Dr. Tuomas Waltimo

E-Mail Website
Guest Editor
Department of Oral Health & Medicine, University Center for Dental Medicine Basel, University of Basel, 4001 Basel, Switzerland
Interests: antibiotics; disinfection; infection; oral health; prevention

Special Issue Information

Dear Colleagues,

Dentistry Journal is very pleased to host a Special Issue honoring Professor Jukka H. Meurman for his outstanding achievements in the association between oral infections and general health.

Dr. Meurman is professor emeritus of oral infectious diseases at the University of Helsinki and head physician at the Department of Oral and Maxillofacial Diseases, Helsinki University Hospital, Finland. He is the author or co-author of hundreds of peer-reviewed original research publications, several textbooks and textbook chapters, mainly focusing on the various aspects of oral health and systemic health and in oral microbiology. He has received several honours and science awards like the Distinguished Scientist Award by the International Association for Dental Research (IADR). Dr. Meurman is Doctor honoris causa in the Louis Pasteur University, Strasbourg, France (2004), the Karolinska Institute, Stockholm, Sweden (2007), and the Medical University of Plovdiv, Bulgaria (2009).  He is member ad hominis of the Royal Society of Surgeons, Edinburgh (FDSRCS), and invited member of the German Leopoldina National Academy of Sciences (ML). He is currently Chair of the Finnish Society of Sciences and Letters and President of the Council of Finnish Academies. He is member of the Executive Committee for Health of the Inter-Academies Platform (IAP). Dr. Meurman was President of the IADR in 2016–2017.  He is an assessor of research and education at several universities: Dresden, Geneva, Karolinska Institute (Stockholm), Oslo, Amsterdam, Turku, Basel, Hong Kong and Singapore.

Since the late 1980s the role of oral infections in systemic diseases has been discussed in a magnitude of research reports—although the concept as such derives from Ancient Egypt. Modern research has shown statistical associations between poor oral health and many systemic diseases. Periodontitis and cardiovascular diseases have been an especially hot topic in this regard. However, it seems that oral infections may provide a link to practically all systemic diseases studied. For example, recent investigations have explored these associations in connection with malignancies and dementia where also respective significant associations have been found. The common nominator in all these entities is the low-grade chronic inflammation triggered by oral and dental infections. The upregulation of cytokines and inflammatory mediators both locally and systemically explains the end-organ pathology, such as atherosclerosis or malignant transformation. The present series of articles summarizes current knowledge about oral infections and various systemic diseases, while also discussing questions of causality.

Dentistry Journal is inviting papers covering innovative scientific/clinical research, reviews, articles from all relevant fields of oral health and systemic health.

Prof. Dr. Jukka H. Meurman
Prof. Dr. Yrsa Le Bell
Prof. Dr. Tuomas Waltimo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Dentistry Journal is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oral infections
  • periodontal disease
  • general health
  • pathogenic mechanisms

Published Papers (6 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

Jump to: Review, Other

11 pages, 817 KiB  
Article
Association between Periodontal Treatment and Healthcare Costs in Patients with Coronary Heart Disease: A Cohort Study Based on German Claims Data
by Katja Blaschke, Martin Hellmich, Christina Samel, Stefan Listl and Ingrid Schubert
Dent. J. 2022, 10(7), 133; https://0-doi-org.brum.beds.ac.uk/10.3390/dj10070133 - 13 Jul 2022
Cited by 1 | Viewed by 1858
Abstract
There is empirical evidence of an association between periodontitis and coronary heart disease (CHD). However, it is uncertain whether periodontal treatment in CHD patients might lead to reduced healthcare costs. This study aims to assess the association between periodontal treatment and healthcare costs [...] Read more.
There is empirical evidence of an association between periodontitis and coronary heart disease (CHD). However, it is uncertain whether periodontal treatment in CHD patients might lead to reduced healthcare costs. This study aims to assess the association between periodontal treatment and healthcare costs in newly diagnosed CHD patients. Data from 21,263 adults who were continuously insured between 2011 and 2016 and who were newly diagnosed with CHD in 2013 were selected from a German claims database. The study population was differentiated by the utilization of periodontal treatment. The average treatment effect (ATE) of periodontal treatment on healthcare costs (total, inpatient, outpatient, drugs) was investigated using weighted Poisson regression models conditional on covariates and is shown as a ratio (of geometric means). Periodontal treatment was documented for 4.7% of the persons in the study population. Newly diagnosed CHD patients showed an ATE of 0.98 for total healthcare cost (95% CI 0.90–1.06), 0.79 for inpatient costs (95% CI 0.61–1.04), and 0.95 for drug costs (95% CI 0.87–1.04). A statistically significant 7% increase in outpatient costs was shown (95% CI 1.01–1.13). Despite a lack of statistical significance in most cases, the study provides evidence of a meaningful decrease in inpatient costs after periodontal treatment. Further studies are needed. Full article
(This article belongs to the Special Issue Research in Oral Health and Systemic Health: A Themed Issue Honoring Professor Jukka H. Meurman)
►▼ Show Figures

Graphical abstract

Review

Jump to: Research, Other

11 pages, 1101 KiB  
Review
On the Role of Dietary Nitrate in the Maintenance of Systemic and Oral Health
by Ulrich Schlagenhauf
Dent. J. 2022, 10(5), 84; https://0-doi-org.brum.beds.ac.uk/10.3390/dj10050084 - 13 May 2022
Cited by 2 | Viewed by 3192
Abstract
The assessment of the significance of nitrates ingested with food has undergone a fundamental change in recent years after many controversial discussions. While for a long time, a diet as low in nitrates as possible was advocated on the basis of epidemiological data [...] Read more.
The assessment of the significance of nitrates ingested with food has undergone a fundamental change in recent years after many controversial discussions. While for a long time, a diet as low in nitrates as possible was advocated on the basis of epidemiological data suggesting a cancer-promoting effect of nitrate-rich diets, more recent findings show that dietary nitrate, after its conversion to nitrite by nitrate-reducing bacteria of the oral microbiota, is an indispensable alternative source for the formation of nitric oxide (NO), which comprises a key element in the physiology of a variety of central body functions such as blood pressure control, defense against invading bacteria and maintenance of a eubiotic microbiota in the gut and oral cavity. This compact narrative review aims to present the evidence supported by clinical and in vitro studies on the ambivalent nature of dietary nitrates for general and oral health and to explain how the targeted adjuvant use of nitrate-rich diets could open new opportunities for a more cause-related control of caries and periodontal disease. Full article
(This article belongs to the Special Issue Research in Oral Health and Systemic Health: A Themed Issue Honoring Professor Jukka H. Meurman)
►▼ Show Figures

Figure 1

8 pages, 733 KiB  
Review
The Stockholm Study: Over 30 years’ Observation of the Effect of Oral Infections on Systemic Health
by Jukka H. Meurman and Birgitta Söder
Dent. J. 2022, 10(4), 68; https://0-doi-org.brum.beds.ac.uk/10.3390/dj10040068 - 13 Apr 2022
Cited by 2 | Viewed by 2316
Abstract
The Stockholm Studies are a series of investigations started in 1985 and still ongoing. Out of 105,798 inhabitants, aged 30 and 40 years and living in the greater Stockholm area in Sweden, 3273 subjects were randomly selected. Of them, 1676 were clinically examined [...] Read more.
The Stockholm Studies are a series of investigations started in 1985 and still ongoing. Out of 105,798 inhabitants, aged 30 and 40 years and living in the greater Stockholm area in Sweden, 3273 subjects were randomly selected. Of them, 1676 were clinically examined focusing on oral health. The subjects were then followed up using national population and health registers in order to study associations between oral health parameters and systemic health outcomes and finally death. The 35 years of observation provides unique possibilities to analyze, for example, how periodontitis links to a number of systemic health issues. The results have consequently provided numerous new associations and confirmed earlier observations on how poor oral health is associated with heart diseases and cancer. Full article
(This article belongs to the Special Issue Research in Oral Health and Systemic Health: A Themed Issue Honoring Professor Jukka H. Meurman)
►▼ Show Figures

Graphical abstract

14 pages, 1284 KiB  
Review
Oral Health and Liver Disease: Bidirectional Associations—A Narrative Review
by Fredrik Åberg and Jaana Helenius-Hietala
Dent. J. 2022, 10(2), 16; https://0-doi-org.brum.beds.ac.uk/10.3390/dj10020016 - 21 Jan 2022
Cited by 6 | Viewed by 7074
Abstract
Several links between chronic liver disease and oral health have been described and are discussed in this narrative review. Oral manifestations such as lichen planus, ulcers, xerostomia, erosion and tongue abnormalities seem to be particularly prevalent among patients with chronic liver disease. These [...] Read more.
Several links between chronic liver disease and oral health have been described and are discussed in this narrative review. Oral manifestations such as lichen planus, ulcers, xerostomia, erosion and tongue abnormalities seem to be particularly prevalent among patients with chronic liver disease. These may be causal, coincidental, secondary to therapeutic interventions, or attributable to other factors commonly observed in liver disease patients. In addition, findings from both experimental and epidemiological studies suggest that periodontitis can induce liver injury and contribute to the progression of chronic liver disease through periodontitis-induced systemic inflammation, endotoxemia, and gut dysbiosis with increased intestinal translocation. This has brought forward the hypothesis of an oral-gut-liver axis. Preliminary clinical intervention studies indicate that local periodontal treatments may lead to beneficial liver effects, but more human studies are needed to clarify if treatment of periodontitis truly can halt or reverse progression of liver disease and improve liver-related outcomes. Full article
(This article belongs to the Special Issue Research in Oral Health and Systemic Health: A Themed Issue Honoring Professor Jukka H. Meurman)
►▼ Show Figures

Figure 1

Other

Jump to: Research, Review

4 pages, 211 KiB  
Commentary
A Commentary on the Potential Use of Oral Microbiome in Prediction, Diagnosis or Prognostics of a Distant Pathology
by Egija Zaura
Dent. J. 2022, 10(9), 156; https://0-doi-org.brum.beds.ac.uk/10.3390/dj10090156 - 24 Aug 2022
Cited by 2 | Viewed by 1483
Abstract
In health, the oral microbiome is in balance with its host. If this balance is lost, this symbiosis is replaced by dysbiotic microbial communities, which are thought to affect the rest of the body either directly or via metabolites or pro-inflammatory molecules. The [...] Read more.
In health, the oral microbiome is in balance with its host. If this balance is lost, this symbiosis is replaced by dysbiotic microbial communities, which are thought to affect the rest of the body either directly or via metabolites or pro-inflammatory molecules. The association of oral microbiome with general health has led to attempts to use oral microbial biomarkers for the prediction, diagnosis or prognosis of distant pathologies such as colorectal carcinoma or pancreatic cancer. These attempts however have no chance to succeed if the complexity of the oral ecosystem and the interplay of environmental, behavioral and biological factors is not taken into account. Standardized, well-documented oral sample collection procedures together with detailed clinical oral examination and behavioral data are the prerequisites for the successful evaluation of the oral microbiome as a potential biomarker for distant pathologies. Full article
(This article belongs to the Special Issue Research in Oral Health and Systemic Health: A Themed Issue Honoring Professor Jukka H. Meurman)
11 pages, 1503 KiB  
Case Report
Post-Operative Bleeding Complications in a Periodontitis Patient Testing Positive for COVID-19
by Georgios Loukas, Madeline X. F. Kosho, Spiros Paraskevas and Bruno G. Loos
Dent. J. 2022, 10(6), 110; https://0-doi-org.brum.beds.ac.uk/10.3390/dj10060110 - 14 Jun 2022
Viewed by 2138
Abstract
Recent scientific evidence states that a subset of COVID-19 patients may have a risk of increased bleeding tendency. This case report presents a healthy 38-year-old woman with generalized stage III, grade C periodontitis with an abnormal post-operative blood clot formation who tested positive [...] Read more.
Recent scientific evidence states that a subset of COVID-19 patients may have a risk of increased bleeding tendency. This case report presents a healthy 38-year-old woman with generalized stage III, grade C periodontitis with an abnormal post-operative blood clot formation who tested positive for COVID-19 after a standard periodontal surgery. Previously, two periodontal surgeries proceeded without any complications and were considered standard. On day one after the third periodontal surgery the patient had no complaints. On day two the patient reported excess bleeding in the oral cavity from the operated area simultaneously with fever and loss of taste. On day three the patient was seen in our clinic; general malaise symptoms and bleeding tendency had started to decline and the patient received a COVID-19 PCR test. At day four the test resulted positive, and she reported no further complaints of intraoral bleeding. Six months later the taste of the patient was still distorted. For this patient with free medical anamnesis, we suggest that the patient had increased plasma levels of tissue plasminogen activator during the crucial postoperative period due to an acute COVID-19 infection. This led to increased plasmin levels with a hyper-fibrinolytic state as a consequence. Full article
(This article belongs to the Special Issue Research in Oral Health and Systemic Health: A Themed Issue Honoring Professor Jukka H. Meurman)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-6
Back to TopTop