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Dentistry Journal
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The Value of Fluorescence Enhanced Diagnosis and Therapy Guidance in...
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The Value of Fluorescence Enhanced Diagnosis and Therapy Guidance in Dentistry

A special issue of Dentistry Journal (ISSN 2304-6767). This special issue belongs to the section "Restorative Dentistry and Traumatology".

Deadline for manuscript submissions: closed (15 September 2021) | Viewed by 10440

Special Issue Editors

Prof. Dr. Liviu Steier

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Guest Editor
1. Robert Schattner Center, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
2. Federal University of Rio Grande do Sul—UFRGS, Porto Alegre 90035-003, Brazil
3. Center for Transdisciplinary Research (CFTR), Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai 602105, Tamil Nadu, India
Interests: fluorophores; photobiomodulation; photoactivated disinfection; bioactive glass; hypochlorous acid; root canal disinfection; root canal obturation; restorative dentistry; arrested caries; infected dentin; affected dentin; demineralization; remineralization; prosthodontics; peri-implantitis; regeneration
Prof. Dr. Hervé Tassery

E-Mail
Guest Editor
Department of Restorative Dentistry of Marseille Dental School, Aix-Marseille University, 13007 Marseille, France
Interests: Cariology; restorative dentistry; preventive dentistry; dental caries; glass Ionomer cements

Special Issue Information

Dear Colleagues,

Bioluminescence has successfully created benefits for in vitro research as well as for bioimaging in diagnosis, guidance, and monitoring of treatment goal achievement. Different light sources and a great selection of endogenous and exogenous fluorophores prove to be a highly valuable addition.

Fluorescence currently finds its application in clinical dentistry in resin curing, caries diagnosis, activity monitoring, diseased tissue removal guidance, plaque and calculus identification and removal, mucosal and tumor diagnosis, and fluorescence-guided surgery. Photoactivated disinfection and photobiomodulation round up the spectrum of use.

This Special Issue welcomes submissions covering fluorescence-guided surgery and enhanced theragnosis (diagnosis and treatment guidance) in all the clinical specialties as well as for photoactivated disinfection and photobiomodulation.

Prof. Dr. Liviu Steier
Prof. Dr. Hervé Tassery
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Dentistry Journal is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Fluorescence Enhanced Theragnosis
  • photoactivated disinfection
  • photo biomodulation
  • endo/exogenous fluorophores
  • caries
  • active caries
  • arrested caries
  • demineralization
  • remineralization
  • plaque
  • calculus
  • peri-implantitis
  • periodontitis
  • early tumor detection
  • tumor margins
  • oral squamous cell carcinoma
  • leukoplakia

Published Papers (3 papers)

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14 pages, 8262 KiB  
Article
Autofluorescence Detection Method for Dental Plaque Bacteria Detection and Classification: Example of Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, and Streptococcus mutans
by Yung-Jhe Yan, Bo-Wen Wang, Chih-Man Yang, Ching-Yi Wu and Mang Ou-Yang
Dent. J. 2021, 9(7), 74; https://0-doi-org.brum.beds.ac.uk/10.3390/dj9070074 - 22 Jun 2021
Cited by 10 | Viewed by 3670
Abstract
The use of fluorescence spectroscopy for plaque detection is a fast and effective way to monitor oral health. At present, there is no uniform specification for the design of the excitation light source of related products for generating fluorescence. To carry out experiments [...] Read more.
The use of fluorescence spectroscopy for plaque detection is a fast and effective way to monitor oral health. At present, there is no uniform specification for the design of the excitation light source of related products for generating fluorescence. To carry out experiments on dental plaque, the fluorescence spectra of three different bacterial species (Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, and Streptococcus mutans) were measured by hyperspectral imaging microscopy (HIM). Three critical issues were found in the experiments. One issue was the unwanted spectrum generated from a mercury line source; two four-order low-pass filters were evaluated for eliminating the unwanted spectrum and meet the experimental requirements. The second issue was the red fluorescence generated from the microscope slide made of borosilicate glass; this could affect the observation of the red fluorescence from the bacteria; quartz microscope slides were found to reduce the fluorescence intensity by about 2 dB compared with the borosilicate slide. The third issue of photobleaching in the fluorescence of the Porphyromonas gingivalis was studied. This study proposes a method of classifying three bacteria based on the spectral intensity ratios (510/635 and 500/635 nm) under the 405 nm excitation light was proposed in this study. The sensitivity and specificity of the classification were approximately 99% and 99%, respectively. Full article
(This article belongs to the Special Issue The Value of Fluorescence Enhanced Diagnosis and Therapy Guidance in Dentistry)
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7 pages, 1023 KiB  
Perspective
Benefits of Using Fluorescence Induced Theragnosis in Fixed Orthodontic Therapy: Status, Technology and Future Trends
by Anand Marya, Liviu Steier, Mohmed Isaqali Karobari and Adith Venugopal
Dent. J. 2021, 9(8), 90; https://0-doi-org.brum.beds.ac.uk/10.3390/dj9080090 - 05 Aug 2021
Cited by 3 | Viewed by 2677
Abstract
Dental biofilm is often found to be the source of bacteria that releases toxins, peptides, lipopolysaccharides as well as organic acids, which lead to gingival inflammation and tooth caries. Further, the persistent plaque may result in the continued destruction of the surrounding soft [...] Read more.
Dental biofilm is often found to be the source of bacteria that releases toxins, peptides, lipopolysaccharides as well as organic acids, which lead to gingival inflammation and tooth caries. Further, the persistent plaque may result in the continued destruction of the surrounding soft and hard tissues. During fixed orthodontic therapy, arch-wires, brackets, and elastic modules have been shown to be sites of significant plaque accumulation, making it difficult for a patient to maintain proper oral hygiene. The problem most dentists face is that they cannot visualize this biofilm completely to be able to carry out efficient plaque removal. Visual assessment is, to date, the most common method for plaque visualization, and various indexes have been demonstrated to be sufficient for quantification of the amount of plaque present. However, the problem is that visual assessments are inconsistent, operator dependent and often subjective, which can lead to inconsistency in results. Fluorescence is one such method that can be explored for its use in effective plaque identification and removal. Literature has it that dentists and patients find it particularly useful for monitoring oral hygiene status during treatment. Fluorescence has the capability of offering clinical orthodontists and researchers a new method of detection of demineralization during orthodontic treatment, furthermore, for efficient removal of orthodontic adhesive cements, fluorescent light may be used in conjunction with high-speed burs to deliver fast, less time consuming, and safer results. The benefit of direct visual treatment using fluorescence enhanced theragnosis is that the patient receives controlled and guided therapy. It has multiple benefits, such as early diagnosis of caries, biofilm identification, and even helps to achieve improved treatment outcomes by better resin selection for esthetic procedures. Full article
(This article belongs to the Special Issue The Value of Fluorescence Enhanced Diagnosis and Therapy Guidance in Dentistry)
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9 pages, 764 KiB  
Perspective
Diagnosis of Biofilm-Associated Peri-Implant Disease Using a Fluorescence-Based Approach
by Geelsu Hwang, Markus B. Blatz, Mark S. Wolff and Liviu Steier
Dent. J. 2021, 9(3), 24; https://0-doi-org.brum.beds.ac.uk/10.3390/dj9030024 - 27 Feb 2021
Cited by 2 | Viewed by 2688
Abstract
Dental implants have become a routine component of daily dental practice and the demand for dental implants is expected to increase significantly in the future. Despite the high success rates of dental implants, failures do occur, resulting in discomfort, rampant destruction of the [...] Read more.
Dental implants have become a routine component of daily dental practice and the demand for dental implants is expected to increase significantly in the future. Despite the high success rates of dental implants, failures do occur, resulting in discomfort, rampant destruction of the oral health, or painful and costly surgical replacement of a failed implant. Peri-implant diseases are inflammatory conditions affecting the soft/hard tissues surrounding a functional dental implant. Plenty of experimental evidence indicates that the accumulation of dental plaque at the soft tissue–implant interface and the subsequent local inflammatory response seems to be key in the pathogenesis of the peri-implant mucositis. Such peri-implant–soft tissue interface is less effective than natural teeth in resisting bacterial invasion, enhancing vulnerability to subsequent peri-implant disease. Furthermore, in certain individuals, it will progress to peri-implantitis, resulting in alveolar bone loss and implant failure. Although early diagnosis and accurate identification of risk factors are extremely important to effectively prevent peri-implant diseases, current systematic reviews revealed that a uniform classification and diagnostic methodology for peri-implantitis are lacking. Recent progress on fluorescence-based technology enabled rapid diagnosis of the disease and effective removal of plaques. Here, we briefly review biofilm-associated peri-implant diseases and propose a fluorescence-based approach for more accurate and objective diagnoses. A fluorescence-based diagnosis tool through headlights combined with special-filtered dental loupes may serve as a hands-free solution for both precise diagnosis and effective removal of plaque-biofilms. Full article
(This article belongs to the Special Issue The Value of Fluorescence Enhanced Diagnosis and Therapy Guidance in Dentistry)
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