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Diagnostics
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Application of 3D-Imaging in Diagnosis
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Application of 3D-Imaging in Diagnosis

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: closed (30 April 2022) | Viewed by 9375

Special Issue Editor

Dr. Ritsuko Kimata Pooh

E-Mail Website
Guest Editor
LLB Fetal Diagnostic Center, Fetal Brain Center, Clinical Research Institute of Fetal Medicine PMC, 1-24, Uehommachi, 7, Tennoji, Osaka 543-0001, Japan
Interests: ultrasound imaging; imaging; diagnostic imaging; prenatal diagnosis; sonoembryology; neuroimaging; neurosonogenetics; medical imaging; 3D-imaging; computed tomography; magnetic resonance; diagnostic radiology; molecular genetics; next-generation sequencing
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Prenatal imaging diagnostic technologies contain sonography, magnetic resonance imaging (MRI), and computed tomography (CT). Conventionally, prenatal diagnostic imaging has been performed on a two-dimensional planar image. Owing to the 3D-imaging approach, however, it has been possible to demonstrate more comprehensive three-dimensional structures and make accurate diagnoses of congenital fetal diseases in utero. Fetal sonographic imaging has been amazingly advanced in recent decades, and various congenital anomalies have been visualized from a very early stage. In early pregnancy, sonoembryology has demonstrated small embryos and fetuses well. In mid-pregnancy, detailed sonography has visualized fetal organs' morphology and vascular structures. It is no exaggeration to say that recently advanced sonography significantly contributes to the elucidation of previously unknown fetal neurology.

Furthermore, recent advances in MRI technology are remarkable. Owing to MRI development, the fetal brain's neural fiber tracts have been depicted, and fetal neurodevelopment has gradually become elucidated. Moreover, 3D-CT imaging has dramatically contributed to the demonstration of fetal bony structure and provided more detailed information on fetal skeletal dysplasia.

The purpose of this Special Issue is to cover the latest information on various prenatal 3D-imaging diagnostics by collecting articles that make full use of easy-to-understand illustrations, images, and pictures.

Dr. Ritsuko Kimata Pooh
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • three-dimensional ultrasound
  • three dimensional MRI
  • three dimensional CT
  • prenatal diagnostics
  • fetus
  • congenital anomaly

Published Papers (4 papers)

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Research

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10 pages, 2701 KiB  
Article
Evaluation of Accuracy and Performance of a Novel, Fully Gantry Integrated 3D Laser System for Computed Tomography Guided Needle Placement: A Phantom Study
by Katharina Weigel, Rahel A. Kubik-Huch, Matthias Baer-Beck, Christian Canstein and Michael Kostrzewa
Diagnostics 2023, 13(2), 282; https://0-doi-org.brum.beds.ac.uk/10.3390/diagnostics13020282 - 12 Jan 2023
Cited by 1 | Viewed by 1819
Abstract
The purpose of this phantom study was to compare the accuracy, speed and technical performance of CT guided needle placement using a conventional technique versus a novel, gantry integrated laser guidance system for both an expert and a novice. A total of 80 [...] Read more.
The purpose of this phantom study was to compare the accuracy, speed and technical performance of CT guided needle placement using a conventional technique versus a novel, gantry integrated laser guidance system for both an expert and a novice. A total of 80 needle placements were performed in an abdominal phantom using conventional CT guidance and a laser guidance system. Analysis of pooled results of expert and novice showed a significant reduction of time (277 vs. 204 s, p = 0.001) and of the number of needle corrections (3.28 vs. 1.58, p < 0.001) required when using laser guidance versus conventional technique. No significant improvement in absolute (3.81 vs. 3.41 mm, p = 0.213) or angular deviation (2.85 vs. 2.18°, p = 0.079) was found. With either approach, the expert was significantly faster (conventional guidance: 207 s vs. 346 s, p < 0.001; laser guidance: 144 s vs. 264 s, p < 0.001) and required fewer needle corrections (conventional guidance: 4 vs. 3, p = 0.027; laser guidance: 2 vs. 1, p = 0.001) than the novice. The laser guidance system helped both the expert and the novice to perform CT guided interventions in a phantom faster and with fewer needle corrections compared to the conventional technique, while achieving similar accuracy. Full article
(This article belongs to the Special Issue Application of 3D-Imaging in Diagnosis)
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12 pages, 2371 KiB  
Article
3D Occlusal Tooth Wear Assessment in Presence of Limited Changes in Non-Occlusal Surfaces
by Nikolaos Gkantidis, Konstantinos Dritsas, Christos Katsaros, Demetrios Halazonetis and Yijin Ren
Diagnostics 2021, 11(6), 1033; https://0-doi-org.brum.beds.ac.uk/10.3390/diagnostics11061033 - 04 Jun 2021
Cited by 7 | Viewed by 2128
Abstract
The study aimed to develop an accurate and convenient 3D occlusal tooth wear assessment technique, applicable when surfaces other than the occlusal undergo changes during the observation period. Various degrees of occlusal tooth wear were simulated in vitro on 18 molar and 18 [...] Read more.
The study aimed to develop an accurate and convenient 3D occlusal tooth wear assessment technique, applicable when surfaces other than the occlusal undergo changes during the observation period. Various degrees of occlusal tooth wear were simulated in vitro on 18 molar and 18 premolar plaster teeth. Additionally, their buccal and lingual surfaces were gently grinded to induce superficial changes and digital dental models were generated. The grinded and the original tooth crowns were superimposed using six different 3D techniques (two reference areas with varying settings; gold standard: GS). Superimposition on intact structures provided the GS measurements. Tooth wear volume comprised the primary outcome measure. All techniques differed significantly to each other in their accuracy (p < 0.001). The technique of choice (CCD: complete crown with 30% estimated overlap of meshes) showed excellent agreement with the GS technique (median difference: 0.045, max: 0.219 mm3), no systematic error and sufficient reproducibility (max difference < 0.040 mm3). Tooth type, tooth alignment in the dental arches, and amount of tooth wear did not significantly affect the results of the CCD technique (p > 0.01). The suggested occlusal tooth wear assessment technique is straightforward and offers accurate outcomes when limited morphological changes occur on surfaces other than the occlusal. Full article
(This article belongs to the Special Issue Application of 3D-Imaging in Diagnosis)
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Review

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11 pages, 1194 KiB  
Review
Utilizing 3D Arterial Spin Labeling to Identify Cerebrovascular Leak and Glymphatic Obstruction in Neurodegenerative Disease
by Charles R. Joseph
Diagnostics 2021, 11(10), 1888; https://0-doi-org.brum.beds.ac.uk/10.3390/diagnostics11101888 - 13 Oct 2021
Cited by 7 | Viewed by 1991
Abstract
New approaches are required to successfully intervene therapeutically in neurodegenerative diseases. Addressing the earliest phases of disease, blood brain barrier (BBB) leak before the accumulation of misfolded proteins has significant potential for success. To do so, however, a reliable, noninvasive and economical test [...] Read more.
New approaches are required to successfully intervene therapeutically in neurodegenerative diseases. Addressing the earliest phases of disease, blood brain barrier (BBB) leak before the accumulation of misfolded proteins has significant potential for success. To do so, however, a reliable, noninvasive and economical test is required. There are two potential methods of identifying the BBB fluid leak that results in the accumulation of normally excluded substances which alter neuropil metabolism, protein synthesis and degradation with buildup of misfolded toxic proteins. The pros and cons of dynamic contrast imaging (DCI or DCE) and 3D TGSE PASL are discussed as potential early identifying methods. The results of prior publications of the 3D ASL technique and an overview of the associated physiologic challenges are discussed. Either method may serve well as reliable physiologic markers as novel therapeutic interventions directed at the vasculopathy of early neurodegenerative disease are developed. They may serve well in addressing other neurologic diseases associated with either vascular leak and/or reduced glymphatic flow. Full article
(This article belongs to the Special Issue Application of 3D-Imaging in Diagnosis)
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15 pages, 1597 KiB  
Review
A 10-Year Retrospective Review of Prenatal Applications, Current Challenges and Future Prospects of Three-Dimensional Sonoangiography
by Tuangsit Wataganara, Thanapa Rekhawasin, Nalat Sompagdee, Sommai Viboonchart, Nisarat Phithakwatchara and Katika Nawapun
Diagnostics 2021, 11(8), 1511; https://0-doi-org.brum.beds.ac.uk/10.3390/diagnostics11081511 - 21 Aug 2021
Cited by 4 | Viewed by 2387
Abstract
Realistic reconstruction of angioarchitecture within the morphological landmark with three-dimensional sonoangiography (three-dimensional power Doppler; 3D PD) may augment standard prenatal ultrasound and Doppler assessments. This study aimed to (a) present a technical overview, (b) determine additional advantages, (c) identify current challenges, and (d) [...] Read more.
Realistic reconstruction of angioarchitecture within the morphological landmark with three-dimensional sonoangiography (three-dimensional power Doppler; 3D PD) may augment standard prenatal ultrasound and Doppler assessments. This study aimed to (a) present a technical overview, (b) determine additional advantages, (c) identify current challenges, and (d) predict trajectories of 3D PD for prenatal assessments. PubMed and Scopus databases for the last decade were searched. Although 307 publications addressed our objectives, their heterogeneity was too broad for statistical analyses. Important findings are therefore presented in descriptive format and supplemented with the authors’ 3D PD images. Acquisition, analysis, and display techniques need to be personalized to improve the quality of flow-volume data. While 3D PD indices of the first-trimester placenta may improve the prediction of preeclampsia, research is needed to standardize the measurement protocol. In highly experienced hands, the unique 3D PD findings improve the diagnostic accuracy of placenta accreta spectrum. A lack of quality assurance is the central challenge to incorporating 3D PD in prenatal care. Machine learning may broaden clinical translations of prenatal 3D PD. Due to its operator dependency, 3D PD has low reproducibility. Until standardization and quality assurance protocols are established, its use as a stand-alone clinical or research tool cannot be recommended. Full article
(This article belongs to the Special Issue Application of 3D-Imaging in Diagnosis)
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