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Diagnostics
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A Leading Diagnostics Tool: Endoscopy 2022
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A Leading Diagnostics Tool: Endoscopy 2022

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 17129

Special Issue Editor

Prof. Dr. Costin Teodor Streba

E-Mail Website
Guest Editor
Department of Research Methodology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania
Interests: diagnosis and histological image analysis in liver and pancreatic disease
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Since its introduction in the mid-19th century, endoscopy has proven an indispensable tool for physicians in almost all medical fields. Serving both medical and surgical patients, in exploratory or interventional settings, endoscopic methods are successfully applied at virtually any age, irrespective of associated pathologies or health status. Yearly advancements in classic techniques, corroborated with innovative new methods to examine tissue and apply curative procedures, have significantly increased life expectancy and general health status worldwide. From gastroenterology or pulmonology, to virtually all surgical branches and even spanning neurology or rheumatology, direct tissue interaction through endoscopy can address all the major medical problems of the 21st century.  

This Special Issue will focus on novel endoscopic devices, techniques, and procedures developed in recent years for both diagnostic and minimally invasive curative procedures, in a diverse array of medical fields and settings.

Prof. Dr. Costin Teodor Streba
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

 

Keywords

  • endoscopic procedures
  • endoscopic techniques
  • diagnostic
  • interventional procedures

Published Papers (4 papers)

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Research

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11 pages, 1373 KiB  
Article
Efficacy of Endobiliary Radiofrequency Ablation in Preserving Survival, Performance Status and Chemotherapy Eligibility of Patients with Unresectable Distal Cholangiocarcinoma: A Case-Control Study
by Vasile Sandru, Bogdan Silviu Ungureanu, Madalina Stan-Ilie, Ruxandra Oprita, Gheorghe G. Balan, Oana-Mihaela Plotogea, Ecaterina Rinja, Andreea Butuc, Afrodita Panaitescu, Alexandru Constantinescu, Dan Ionut Gheonea and Gabriel Constantinescu
Diagnostics 2022, 12(8), 1804; https://0-doi-org.brum.beds.ac.uk/10.3390/diagnostics12081804 - 26 Jul 2022
Cited by 4 | Viewed by 1869
Abstract
Background: Cholangiocarcinoma is the most common malignancy of the bile ducts causing intrahepatic, hilar, or distal bile duct obstruction. Most jaundiced patients are diagnosed with unresectable tumors in need for palliative bile duct drainage and chemotherapy. Endobiliary radiofrequency ablation (RFA) is an adjuvant [...] Read more.
Background: Cholangiocarcinoma is the most common malignancy of the bile ducts causing intrahepatic, hilar, or distal bile duct obstruction. Most jaundiced patients are diagnosed with unresectable tumors in need for palliative bile duct drainage and chemotherapy. Endobiliary radiofrequency ablation (RFA) is an adjuvant technique that may be applied prior to biliary stenting. The aim of our study was to assess the efficacy of endobiliary RFA prior to stent insertion in patients with unresectable distal cholangiocarcinomas. Methods: Twenty-five patients (eight treated with RFA and stenting and 17 treated with stenting alone) were included in a case-controlled study. We prospectively assessed the impact of RFA on the survival rate, the patient performance status, and the preservation of eligibility for chemotherapy based on the patient laboratory profile. Results: Patients treated with RFA prior to stenting proved to have a significantly longer survival interval (19 vs. 16 months, p = 0.04, 95% CI) and significantly better performance status. Moreover, the laboratory profiles of patients treated with RFA has been proven superior in terms of total bilirubin, liver enzymes, and kidney function, thus making patients likely eligible for palliative chemotherapy. Post-ERCP adverse events were scarce in both the study group and the control group. Conclusion: Given the isolated adverse events and the impact on the patient survival, performance, and laboratory profile, RFA can be considered safe and efficient in the management of patients with unresectable distal cholangiocarcinomas. Full article
(This article belongs to the Special Issue A Leading Diagnostics Tool: Endoscopy 2022)
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Review

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13 pages, 924 KiB  
Review
Endoscopic Diagnosis and Management of Barrett’s Esophagus with Low-Grade Dysplasia
by Francesco Maione, Alessia Chini, Rosa Maione, Michele Manigrasso, Alessandra Marello, Gianluca Cassese, Nicola Gennarelli, Marco Milone and Giovanni Domenico De Palma
Diagnostics 2022, 12(5), 1295; https://0-doi-org.brum.beds.ac.uk/10.3390/diagnostics12051295 - 23 May 2022
Cited by 3 | Viewed by 5214
Abstract
Barrett’s Esophagus is a common condition associated with chronic gastroesophageal reflux disease. It is well known that it has an association with a higher incidence of esophageal adenocarcinoma, but this neoplastic transformation is first preceded by the onset of low and high-grade dysplasia. [...] Read more.
Barrett’s Esophagus is a common condition associated with chronic gastroesophageal reflux disease. It is well known that it has an association with a higher incidence of esophageal adenocarcinoma, but this neoplastic transformation is first preceded by the onset of low and high-grade dysplasia. The evaluation of low grade dysplastic esophageal mucosa is still controversial; although endoscopic surveillance is preferred, several minimally invasive endoscopic therapeutic approaches are available. Endoscopic mucosal resection and radiofrequency ablation are the most used endoscopic treatments for the eradication of low-grade dysplasia, respectively, for nodular and flat dysplasia. Novel endoscopic treatments are cryotherapy ablation and argon plasma coagulation, that have good rates of eradication with less complications and post-procedural pain. Full article
(This article belongs to the Special Issue A Leading Diagnostics Tool: Endoscopy 2022)
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16 pages, 1882 KiB  
Review
Endoscopic Imaging Technology Today
by Axel Boese, Cora Wex, Roland Croner, Uwe Bernd Liehr, Johann Jakob Wendler, Jochen Weigt, Thorsten Walles, Ulrich Vorwerk, Christoph Hubertus Lohmann, Michael Friebe and Alfredo Illanes
Diagnostics 2022, 12(5), 1262; https://0-doi-org.brum.beds.ac.uk/10.3390/diagnostics12051262 - 18 May 2022
Cited by 16 | Viewed by 6637
Abstract
One of the most applied imaging methods in medicine is endoscopy. A highly specialized image modality has been developed since the first modern endoscope, the “Lichtleiter” of Bozzini was introduced in the early 19th century. Multiple medical disciplines use endoscopy for diagnostics or [...] Read more.
One of the most applied imaging methods in medicine is endoscopy. A highly specialized image modality has been developed since the first modern endoscope, the “Lichtleiter” of Bozzini was introduced in the early 19th century. Multiple medical disciplines use endoscopy for diagnostics or to visualize and support therapeutic procedures. Therefore, the shapes, functionalities, handling concepts, and the integrated and surrounding technology of endoscopic systems were adapted to meet these dedicated medical application requirements. This survey gives an overview of modern endoscopic technology’s state of the art. Therefore, the portfolio of several manufacturers with commercially available products on the market was screened and summarized. Additionally, some trends for upcoming developments were collected. Full article
(This article belongs to the Special Issue A Leading Diagnostics Tool: Endoscopy 2022)
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Other

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34 pages, 5891 KiB  
Systematic Review
Hepatocellular Carcinoma with Gastrointestinal Involvement: A Systematic Review
by Cristiana Marinela Urhut, Larisa Daniela Sandulescu, Liliana Streba, Vlad Florin Iovanescu, Sarmis Marian Sandulescu and Suzana Danoiu
Diagnostics 2022, 12(5), 1270; https://0-doi-org.brum.beds.ac.uk/10.3390/diagnostics12051270 - 19 May 2022
Cited by 1 | Viewed by 2246
Abstract
In this paper, we aimed to evaluate clinical and imagistic features, and also to provide a diagnostic algorithm for patients presenting with gastrointestinal involvement from hepatocellular carcinoma (HCC). We conducted a systematic search on the PubMed, Scopus and Web of Science databases to [...] Read more.
In this paper, we aimed to evaluate clinical and imagistic features, and also to provide a diagnostic algorithm for patients presenting with gastrointestinal involvement from hepatocellular carcinoma (HCC). We conducted a systematic search on the PubMed, Scopus and Web of Science databases to identify and collect papers oncases of HCC with gastrointestinal involvement. This search was last updated on 29 April 2022. One hundred and twenty-three articles were included, corresponding to 197 patients. The majority of the patients were male (87.30%), with a mean age of 61.21 years old. The analysis showed large HCCs located mainly in the right hepatic lobe, and highly elevated alfa-fetoprotein (mean = 15,366.18 ng/mL). The most frequent etiological factor was hepatitis B virus (38.57%). Portal vein thrombosis was present in 27.91% of cases. HCC was previously treated in most cases by transarterial chemoembolization (32.99%) and surgical resection (28.93%). Gastrointestinal lesions, developed mainly through direct invasion and hematogenous routes, were predominantly detected in the stomach and duodenum in equal measure—27.91%. Gastrointestinal bleeding was the most common presentation (49.74%). The main diagnostic tools were esophagogastroduodenoscopy (EGD) and computed tomography. The mean survival time was 7.30 months. Gastrointestinal involvement in HCC should be included in the differential diagnosis of patients with underlying HCC and gastrointestinal manifestations or pathological findings in EGD. Full article
(This article belongs to the Special Issue A Leading Diagnostics Tool: Endoscopy 2022)
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