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Clinical Diagnosis and Treatment of Mouth Diseases

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A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: closed (31 March 2022) | Viewed by 11270

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Special Issue Editor

Prof. Dr. Massimo Corsalini

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Guest Editor

Department of Interdisciplinary Medicine, University of Bari Aldo Moro, 70124 Bari, Italy
Interests: dental prosthesis; oral pathology; implant dentistry; dental materials; dentures
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Mouth diseases are currently being studied by both dentists and doctors as they are frequently linked to systemic diseases.

An early and accurate diagnosis is important for the treatment of more aggressive diseases. Treatment of mouth diseases can be pharmacological or surgical and can lead to partial loss of the jaw bones. Frequent diseases such as tooth decay and periodontal disease can also require complex treatments. This Special Issue aims to contribute to the correct diagnosis and treatment of mouth diseases, and we welcome submissions on, but not limited to, stomatitis, caries, periodontal disease, oncological diseases, temporomandibular joint pathologies, malocclusions, and all possible therapies.

Prof. Dr. Massimo Corsalini
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

stomatitis
oral cancer
periodontal disease
malocclusions
TMJ diseases
post surgical defects
oral rehabilitation
dental prosthesis
caries
new materials in oral rehabilitation

Published Papers (4 papers)

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Research

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9 pages, 940 KiB

Open AccessCommunication

Impact of Maximum Tongue Pressure in Patients with Jaw Deformities Who Underwent Orthognathic Surgery

by Koichi Koizumi, Tomoaki Shintani, Yuki Yoshimi, Mirai Higaki, Ryo Kunimatsu, Yukio Yoshioka, Kazuhiro Tsuga, Kotaro Tanimoto, Hideki Shiba and Shigeaki Toratani

Diagnostics 2022, 12(2), 404; https://0-doi-org.brum.beds.ac.uk/10.3390/diagnostics12020404 - 04 Feb 2022

Cited by 5 | Viewed by 1469

Abstract

Malocclusion and morphological abnormalities of the jawbone often affect the stomatognathic function and long-term postoperative stability in patients with jaw deformities. There are few reports on the effect of maximum tongue pressure (MTP) in these patients. We investigated the relationship between the MTP and jawbone morphology and the effect of the MTP on surgery in 42 patients with jaw deformity who underwent surgical orthodontic treatment at Hiroshima University Hospital. The MTP was measured using a tongue pressure measurement device; the average value was considered as the MTP. Based on the MTP measured before surgery, patients were classified into the high- or the low-MTP group. The clinical findings and results of the cephalometric analysis were compared. Posterior movement of the mandible in the high-MTP group was significantly lower than that in the low-MTP group. The ANB angle, overjet, and overbite in the high-MTP group were significantly smaller than those in the low-MTP group. On the other hand, there was no difference between the two groups in the measured values, indicating a labial inclination of the anterior teeth (U1 to SN, U1 to FH, IMPA, and FMIA). MTP has been suggested to affect mandibular prognathism in patients with jaw deformities. Full article

(This article belongs to the Special Issue Clinical Diagnosis and Treatment of Mouth Diseases)

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10 pages, 1379 KiB

Open AccessArticle

Dental Disorders and Salivary Changes in Patients with Laryngopharyngeal Reflux

by Sabrina Casciaro, Matteo Gelardi, Rossana Giancaspro, Vitaliano Nicola Quaranta, Giuseppe Porro, Brigida Sterlicchio, Antonia Abbinante and Massimo Corsalini

Diagnostics 2022, 12(1), 153; https://0-doi-org.brum.beds.ac.uk/10.3390/diagnostics12010153 - 09 Jan 2022

Cited by 4 | Viewed by 1387

Abstract

Background: Laryngopharyngeal reflux (LPR) is a common inflammatory condition of the upper aerodigestive tract tissues related to the effects of gastroduodenal content reflux, characterized by a wide variety of clinical manifestations. The aim of our study was to evaluate the possible association between dental disorders and LRP, focusing on the role of salivary changes. Methods: Patient’s dental status was evaluated according to Schiff Index Sensitivity Scale (SISS), Basic Erosive Wear Examination (BEWE) and Decayed, Missing, and Filled Teeth (DMFT) scores. Reflux-associated symptoms were assessed according to Reflux symptom index (RSI). A qualitative and quantitative examination of saliva was performed. Results: Patients suffering from LPR had a higher incidence of dental disorders, regardless the presence of salivary pepsin, and thus, statistically significant higher scores of RSI (p = 0.0001), SISS (p = 0.001), BEWE (p < 0.001) and VAS (p < 0.001). Moreover, they had lower salivary flow compared with healthy patients. Conclusions: The finding of demineralization and dental caries on intraoral evaluation must raise the suspicion of LRP. Reflux treatments should also be aimed at correcting salivary alterations, in order to preserve the buffering capacity and salivary pH, thus preventing mucosal and dental damage. Full article

(This article belongs to the Special Issue Clinical Diagnosis and Treatment of Mouth Diseases)

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8 pages, 2278 KiB

Open AccessArticle

Evaluation of Depth of Invasion and Tumor Thickness as a Prognostic Factor for Early-Stage Oral Squamous Cell Carcinoma: A Retrospective Study

by You-Jung Lee, Tae-Geon Kwon, Jin-Wook Kim, Sung-Tak Lee, Su-Hyung Hong and So-Young Choi

Diagnostics 2022, 12(1), 20; https://0-doi-org.brum.beds.ac.uk/10.3390/diagnostics12010020 - 23 Dec 2021

Cited by 4 | Viewed by 5734

Abstract

The aim of this study was to compare the effect of using depth of invasion (DOI) versus tumor thickness (TT) as a prognostic factor for early-stage oral squamous cell carcinoma (OSCC). A total of 57 patients with early-stage OSCC treated surgically from 2009 to 2014 at our institution were reviewed retrospectively. Histopathological measurement of DOI and TT was performed. The validation of DOI and TT as prognostic factors was conducted using a Kaplan–Meier survival analysis. TT had no association with disease-specific survival (DSS) or progression-free survival (PFS) in this cohort; however, increased DOI was significantly associated with decreased DSS but not correlated to decreased PFS. The T category of the 7th edition of AJCC was statistically associated with both DSS and PFS; however, the T category of the 8th edition of the AJCC was only associated with DSS. In this study group, TT could not be used as a prognostic factor, and DOI was not by itself sufficient to predict prognosis for early-stage OSCC. The T category in AJCC 8th Edition cannot be considered the sole prognostic factor for early OSCC, so additional prognostic factors may need to be considered. Full article

(This article belongs to the Special Issue Clinical Diagnosis and Treatment of Mouth Diseases)

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Other

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6 pages, 1243 KiB

Open AccessCase Report

Dilated Odontoma Arising in the Mandibular Third Molar Germ: Report of a Case of an Unusual Lesion in an Uncommon Site

by Francesca Zara, Giacomo D’Angeli, Alessandro Corsi, Antonella Polimeni and Gian Luca Sfasciotti

Diagnostics 2021, 11(12), 2256; https://0-doi-org.brum.beds.ac.uk/10.3390/diagnostics11122256 - 02 Dec 2021

Cited by 1 | Viewed by 1780

Abstract

Dilated odontoma is the most severe variant of dens invaginatus. It is extremely uncommon in the posterior mandible. It is thought to originate during the morpho-differentiation stage of dental development. However, its etiology and pathogenesis remain obscure. We report here the clinical and pathologic findings of an incidentally discovered dilated odontoma arising in the left third mandibular molar germ of an 11-year-old male and a review of the pertinent literature. As dilated odontoma is not established as an independent entity in the current WHO classification of odontogenic tumors and is the result of a well-established developmental anomaly of the tooth (that is, the invagination of the enamel organ into the dental papilla), it should be better identified as dilated dens invaginatus. Full article

(This article belongs to the Special Issue Clinical Diagnosis and Treatment of Mouth Diseases)

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