Epigenetics of Sleep Disorders

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: closed (28 February 2022) | Viewed by 2797

Special Issue Editor

School of Medicine, University of Missouri, Columbia, MO 65211, USA
Interests: epigenomics; sleep disorders; multiomics; obstructive sleep apnea; developmental origin of diseases; circulating DNA; liquid biopsies; cognitive disorders; cardiometabolic disorders; cancer
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear colleagues,

Sleep disorders are common conditions disturbing sleep patterns in adults and children. They represent a wide spectrum including sleep disruption, insomnia, restless leg syndrome, hypersomnia (e.g., narcolepsy), circadian rhythm disorders, parasomnias, and sleep disordered breathing (e.g., sleep apnea). Sleep disorders entail problems with the quality, timing, and amount of sleep, which result in daytime distress and impairment in functioning. Furthermore, numerous and serious morbidities are associated with sleep disorders, virtually affecting every organ and system. Sleep disorders have been associated with the occurrence of metabolic, cardiovascular, and cognitive disorders, as well as tumor aggressiveness and poor prognosis in cancer.

Epigenetics refers to the study of heritable changes in genome function that occur without a change in DNA sequence. Assessment and evaluation of epigenomic profiles have currently a fundamental role in understanding, diagnosing, and treating complex pathologies. Changes in epigenetic profiles are among the most common molecular alterations in virtually all complex diseases including cancer, diabetes, metabolic syndrome, atherosclerosis, inflammatory bowel disease, autoimmune diseases, and psychiatric and neurodegenerative disorders. The role of epigenetic regulation in sleep disorders is starting to be recognized. New diagnostic opportunities may arise from the identification of epigenetic alterations that may provide high sensitivity and specificity for detecting, monitoring, and predicting the outcome of sleep disorders.

This Special Issue is dedicated to reviewing and presenting new data from current research on the role of epigenetics in the pathophysiology of sleep disorders and the application of epigenetic markers for the diagnosis of sleep disorders and their comorbidities.

You may choose our Joint Special Issue in Neurology International.

Dr. Rene Cortese
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • DNA methylation
  • Histone modifications
  • Non-coding RNA
  • Epigenetics
  • Sleep disorders
  • Molecular diagnostics

Published Papers (1 paper)

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Editorial

4 pages, 214 KiB  
Editorial
Epigenetics of Sleep Disorders: An Emerging Field in Diagnosis and Therapeutics
by Rene Cortese
Diagnostics 2021, 11(5), 851; https://0-doi-org.brum.beds.ac.uk/10.3390/diagnostics11050851 - 10 May 2021
Cited by 3 | Viewed by 2079
Abstract
The role of epigenetic regulation in sleep disorders is starting to be recognized [...] Full article
(This article belongs to the Special Issue Epigenetics of Sleep Disorders)
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