Special Issue "Gastrointestinal Tract Inflammation and Cancers"
Deadline for manuscript submissions: 26 April 2022.
Interests: abdominal pain; bloating; bloody stool; celiac disease; Clostridium difficile colitis (C. diff); constipation; Crohn’s disease; diarrhea; dysphagia; gastroesophageal reflux disease (GERD); hepatitis C; inflammatory bowel disease (IBD); irritable bowel syndrome (IBS); liver diseases; nausea; pancreatitis; nutrition; nausea; vomiting; colon cancer screening
As we have learned from patients with inflammatory bowel disease, untreated chronic inflammation leads to increased risk of colorectal cancers. Although inflammation and its potential tumorogenic effects have been well established in the last two decades, exact molecular mechanisms are still being discovered. Discovery of these pathways will lead to novel therapeutic options. Luminal gastrointestinal cancers arise from pre-malignant lesions, usually in the setting of chronic inflammation leading to dysplastic mucosal changes and, eventually, carcinomas. Gastroesophageal reflux disease and long-standing esophagitis will lead to Barrett's esophagus and subsequently esophageal adenocarcinoma. A similar pathway is applicable for gastric inflammation from H. pylori infection and this chronic inflammation leading to gastric adenocarcinoma. Inflammation cascade can be triggered from environmental factors such as hyperacidity; infectious etiologies such as H. pylori. Underlying genetic factors and increased autoimmunity will also contribute this progression. We are also learning more about the microbiome and its effect on cancer pathogenesis.
In this Special Issue, we would like to increase our knowledge on this exciting field of research in gastrointestinal tract cancers from a multidisciplinary perspective. Understanding the inflammation to carcinoma pathway is a vital step for new discoveries.
This Special Issue "Gastrointestinal Tract Inflammation and Cancers" will play an important role to bring researchers from different fields to share their knowledge.
We welcome your contribution to the Special Issue.
Dr. Veysel Tahan
Dr. Ebubekir S. Daglilar
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Gastrointestinal Tract Inflammation
- H. pylori and Gastric cancer
- Inflammatory bowel disease and Colorectal cancer
- Obesity and inflammation