Epigenomic Regulation during Lung Development and Disease

A special issue of Epigenomes (ISSN 2075-4655).

Deadline for manuscript submissions: closed (1 March 2022) | Viewed by 401

Special Issue Editors


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Guest Editor
Department of Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35487, USA
Interests: epigenetic mechanisms in lung injury, repair, and aging

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Co-Guest Editor
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA
Interests: Pulmonary fibrosis; fibroblast biology; DNA methylation and epigenetic changes in pulmonary fibrosis and other chronic lung diseasesPulmonary fibrosis; DNA methylation and epigenetic changes in pulmonary fibrosis and other chronic lung diseases

Special Issue Information

Dear Colleagues,

Due to the constant exposure to the air and environment, the lungs are primary organs for epigenetic changes. Specific epigenomic patterns in different cell types are critical to the normal development of the lungs. The epigenome can be altered under different conditions of the air/environment, resulting specific lung disease. Alterations in DNA/RNA methylation, histone modifications, and noncoding RNAs have all been shown to play critical roles in the development of various lung diseases including asthma, COPD, pulmonary hypertension, lung cancer, and pulmonary fibrosis. These epigenetic changes affect the expression and regulation of key genes that contribute to the pathogenesis of those disorders. Epigenetic modifiers also have the potential to serve as an untapped area for future therapy.

In this Special Issue of Epigenomes, we intend to collect primary research articles and reviews that explore the impact of epigenetic changes in lung development, pathogenesis of various lung related diseases, and highlighting potential epigenetic drugs for therapy in lung related disorders. We also welcome articles that examine the environmental effects of epigenomic changes in lung disease. With respiratory disorders consisting of half of the top six causes of death in the world, a look at how epigenetics affects lung disease will be critical for basic and clincal researchers to find new approaches and advance treatment for related respiratory diseases.

Dr. Yan Y. Sanders
Guest Editor
Dr. Steven K. Huang
Co-Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Epigenomes is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • lung
  • lung disease
  • epigenetics
  • DNA methylation
  • RNA methylation
  • histone modifications
  • non-coding RNA
  • gene expression
  • gene regulation
  • transcription
  • transcription factor
  • epigenetic modifier

Published Papers

There is no accepted submissions to this special issue at this moment.
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