Special Issue "Epigenetics in Stem Cells and Their Derivatives"
A special issue of Epigenomes (ISSN 2075-4655).
Deadline for manuscript submissions: closed (31 December 2020).
Epigenetic modifications play a key role in the control of gene expression in stem cells.
In vivo, epigenetic modifications, including DNA methylation, histone marks, and non-coding RNAs, are instrumental for lineage commitment of stem cells during development, and for tissue repair by resident stem cells in adult tissues. In addition, epigenetic modifications participate in the loss of identify of stem cells, which accompany tumour development.
In vitro, stem cells are used as models that recapitulate in vivo development, and are a potential source of cells for therapy. However, in vitro culture has a major impact on the epigenetic signature of stem cells and on the quality of their derivatives.
In this Special Issue, we welcome review, research, and method manuscripts covering the following areas:
- Epigenetics status of undifferentiated pluripotent stem cells, and how it compares to the in vivo situation.
- Epigenetics status of the derivatives of pluripotent stem cells, including organoids.
- Influence of epigenetic modifications on the developmental trajectories of stem cells.
- Influence of epigenetic modifications on the repair capacity of tissue-specific stem cells.
- Influence of epigenetic modifications on the loss of identity of stem cells, leading to the emergence of cancer stem cells.
Dr. Tristan Bouschet
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Epigenomes is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.