Occurrence, Importance and Control Strategies of Major Mycotoxins in Foods-Prevention and Detoxification

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Quality and Safety".

Deadline for manuscript submissions: closed (18 June 2021) | Viewed by 34266

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Guest Editor
Department of Food Science and Technology, University of Peloponnese, 24100 Antikalamos, Greece
Interests: food technology; food engineering; food safety; food quality; extra virgin olive oil; mycotoxins; fermented foods
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Guest Editor
Department of Health, Animal Science and Food Safety (VESPA), University of Milan, 20133 Milan, Italy
Interests: antibiotics; PFASs; pesticides; mycotoxins; growth promoters; risk assessment; food safety; food inspection

Special Issue Information

Dear Colleagues,

Mycotoxin contamination is one of the most relevant and worrisome problems concerning food and feed safety, because it can cause a variety of toxic acute and chronic effects in animal and human health. Mycotoxins are fungal toxins produced by fungi, which occur globally in food and feed derivatives, and are produced under certain environmental conditions. Fungi can invade, colonize, and produce mycotoxins either during pre-harvest, or post harvest, during storage, transport, processing, and feeding. Inadequate and bad harvesting practices, and inappropriate drying conditions, handling, packaging ,and storage, contribute to the growth of fungi and increase the risk of producing mycotoxins. The contamination of agricultural products with mycotoxins is an important problem in tropical and subtropical areas, where the climate and bad storage conditions promote fungal growth and the production of mycotoxins. Fungi rank second as a cause of damage during the storage of cereals, while insects rank first. Mycotoxins are found in many types of important agricultural products, such as cereals (wheat, barley, rye, maize, rice, sorghum, and millet), bread, pasta, flour, nuts (peanuts, groundnuts), spices, grapes, currant, wine, beer, dried fruits (figs, dates, plums apricots, and raisins), juices, olives, vegetable oils, and cotton seeds, and also in rations of farm animals resulting in their appearance in milk, eggs, and the meat of these animals, resulting in severe economic loss at all levels of food production. According to FAO, mycotoxins contaminate nearly 25% of the world's agricultural commodities.

Increased knowledge and awareness of consumption of food and feed contaminated with mycotoxins has turned the focus of many investigations into the development of their inactivation and detoxification process in food. Various methods have been investigated in relation to their ability to inactivate mycotoxins in contaminated food and feed. These methods are aimed either at removing the toxin from the product or at its destruction, and are classified into physical, chemical, and biological. Performance and the efficacy of a method for inactivating mycotoxins depends largely on the nature of the product, the content of the product humidity, the type of mycotoxin, the level of infection, and the degree of attachment of mycotoxins with the products.

Adoption of preventive and control methods across all stages of the food supply chain can restrict the entry of mycotoxins and/or control their levels in human and animal systems.

Prof. Dr. Theodoros Varzakas
Dr. Nobile Maria
Guest Editors

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Keywords

  • mycotoxins in foods
  • safety
  • quality
  • detection
  • prevention
  • detoxification

Published Papers (3 papers)

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Research

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12 pages, 604 KiB  
Article
A Study of the Occurrence of Aflatoxin M1 in Milk Supply Chain over a Seven-Year Period (2014–2020): Human Exposure Assessment and Risk Characterization in the Population of Central Italy
by Rossana Roila, Raffaella Branciari, Emanuela Verdini, David Ranucci, Andrea Valiani, Alessandro Pelliccia, Laura Fioroni and Ivan Pecorelli
Foods 2021, 10(7), 1529; https://0-doi-org.brum.beds.ac.uk/10.3390/foods10071529 - 02 Jul 2021
Cited by 17 | Viewed by 2251
Abstract
Aflatoxin food contamination represents a rising global issue that will continue to increase due to climate change. Aflatoxin M1 (AFM1) is of high concern for the whole dairy industry. In light of AFM1′s harmful potential, a human health exposure assessment and risk characterization [...] Read more.
Aflatoxin food contamination represents a rising global issue that will continue to increase due to climate change. Aflatoxin M1 (AFM1) is of high concern for the whole dairy industry. In light of AFM1′s harmful potential, a human health exposure assessment and risk characterization were performed for all age populations of central Italy with regard to milk and cheese consumption by means of the margin of exposure (MOE). In total, 16,934 cow and ewe’s milk samples were collected from 2014 to 2020 and analyzed by an enzyme-linked immunosorbent assay (ELISA) screening method, confirmed by high-performance liquid chromatography with a fluorescence detector (HPLC-FLD). The average concentration of AFM1 in cow’s milk ranged from 0.009 to 0.015 µg/kg, while in ewe’s milk, the average concentration ranged from 0.009 to 0.013 µg/kg. The average amount of AFM1 exposure ranged from 0.00005 to 0.00195 g/kg bw/day, with the main contributor represented by drinking milk, followed by the consumption of soft cheeses. A high level of public health concern related to the youngest consumers has arisen from risk characterizations highlighting the need for constant monitoring of AFM1′s occurrence in milk by inspection authorities, alongside regular updates with regard to exposure assessments. Full article
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Review

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23 pages, 296 KiB  
Review
Advances in Analysis and Detection of Major Mycotoxins in Foods
by Sofia Agriopoulou, Eygenia Stamatelopoulou and Theodoros Varzakas
Foods 2020, 9(4), 518; https://0-doi-org.brum.beds.ac.uk/10.3390/foods9040518 - 20 Apr 2020
Cited by 104 | Viewed by 11676
Abstract
Mycotoxins are the most widely studied biological toxins, which contaminate foods at very low concentrations. This review describes the emerging extraction techniques and the current and alternatives analytical techniques and methods that have been used to successfully detect and identify important mycotoxins. Some [...] Read more.
Mycotoxins are the most widely studied biological toxins, which contaminate foods at very low concentrations. This review describes the emerging extraction techniques and the current and alternatives analytical techniques and methods that have been used to successfully detect and identify important mycotoxins. Some of them have proven to be particularly effective in not only the detection of mycotoxins, but also in detecting mycotoxin-producing fungi. Chromatographic techniques such as high-performance liquid chromatography coupled with various detectors like fluorescence, diode array, UV, liquid chromatography coupled with mass spectrometry, and liquid chromatography-tandem mass spectrometry, have been powerful tools for analyzing and detecting major mycotoxins. Recent progress of the development of rapid immunoaffinity-based detection techniques such as immunoassays and biosensors, as well as emerging technologies like proteomic and genomic methods, molecular techniques, electronic nose, aggregation-induced emission dye, quantitative NMR and hyperspectral imaging for the detection of mycotoxins in foods, have also been presented. Full article
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48 pages, 891 KiB  
Review
Advances in Occurrence, Importance, and Mycotoxin Control Strategies: Prevention and Detoxification in Foods
by Sofia Agriopoulou, Eygenia Stamatelopoulou and Theodoros Varzakas
Foods 2020, 9(2), 137; https://0-doi-org.brum.beds.ac.uk/10.3390/foods9020137 - 28 Jan 2020
Cited by 364 | Viewed by 19360
Abstract
Mycotoxins are toxic substances that can infect many foods with carcinogenic, genotoxic, teratogenic, nephrotoxic, and hepatotoxic effects. Mycotoxin contamination of foodstuffs causes diseases worldwide. The major classes of mycotoxins that are of the greatest agroeconomic importance are aflatoxins, ochratoxins, fumonisins, trichothecenes, emerging Fusarium [...] Read more.
Mycotoxins are toxic substances that can infect many foods with carcinogenic, genotoxic, teratogenic, nephrotoxic, and hepatotoxic effects. Mycotoxin contamination of foodstuffs causes diseases worldwide. The major classes of mycotoxins that are of the greatest agroeconomic importance are aflatoxins, ochratoxins, fumonisins, trichothecenes, emerging Fusarium mycotoxins, enniatins, ergot alkaloids, Alternaria toxins, and patulin. Thus, in order to mitigate mycotoxin contamination of foods, many control approaches are used. Prevention, detoxification, and decontamination of mycotoxins can contribute in this purpose in the pre-harvest and post-harvest stages. Therefore, the purpose of the review is to elaborate on the recent advances regarding the occurrence of main mycotoxins in many types of important agricultural products, as well as the methods of inactivation and detoxification of foods from mycotoxins in order to reduce or fully eliminate them. Full article
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