Toxins in Food: Development of New Analytical Methods, Monitoring and Mitigation Strategies

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Toxicology".

Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 7614

Special Issue Editors


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Guest Editor
Department of Health, Animal Science and Food Safety, University of Milan, Via dell’Università 6, 26900 Lodi, Italy
Interests: drug residues and contaminants in animal matrices and foodstuffs; risk characterization

E-Mail Website
Guest Editor
Department of Health, Animal Science and Food Safety, University of Milan, Via dell’Università 6, 26900 Lodi, Italy
Interests: drug residues and contaminants in animal matrices and foodstuffs; risk characterization

Special Issue Information

Dear Colleagues,

The possibility of oral exposure to toxins (e.g. mycotoxins, water biotoxins, plant, bacterial, and mushrooms toxins), i.e., through food and water, represents a serious health concern both for humans and animals. The term toxin indicates a natural substance or a mixture of them that, when at a high enough dose, can affect normal biological processes, causing adverse health effects. By nature, toxins may be physiologically produced by an organism or may be biosynthesized under particular conditions (e.g. environmental stress, selective pressure on certain bacterial strains, and climate change altering ecosystems balance).

Given their high number, the variety of chemical structures and sources from which they are derived as well as the detection of toxins represent analytical challenges. While the development of new sensitive analytical methods is essential in food control, the continuous monitoring of toxin presence in foodstuff must be ensured to obtain the data necessary to characterize the risk for consumers; to estimate the dimension of the problem; and to encourage the development of new mitigation strategies.

Therefore, we invite reviews and research papers focusing on analytical advances in toxins and their metabolites detection, up-to-date monitoring plans concerning their occurrence in foodstuffs, risk assessment studies, and discussions of novel mitigation approaches.

Prof. Dr. Francesco Arioli
Dr. Federica Di Cesare
Guest Editors

Keywords

  • toxins
  • screening methods
  • sensors
  • mass spectrometry
  • monitoring plans
  • risk assessment
  • mitigation strategies

Published Papers (2 papers)

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Research

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11 pages, 1425 KiB  
Article
A Novel Fluorescent Aptasensor Based on Real-Time Fluorescence and Strand Displacement Amplification for the Detection of Ochratoxin A
by Wei Guo, Haoyu Yang, Yunzhe Zhang, Hao Wu, Xin Lu, Jianxin Tan and Wei Zhang
Foods 2022, 11(16), 2443; https://0-doi-org.brum.beds.ac.uk/10.3390/foods11162443 - 13 Aug 2022
Cited by 4 | Viewed by 1557
Abstract
It is urgently necessary to develop convenient, reliable, ultrasensitive and specific methods of ochratoxin A determination in food safety owing to its high toxicity. In the present study, an ultrasensitive and labeled-free fluorescent aptamer sensor combining real-time fluorescence with strand displacement amplification (SDA) [...] Read more.
It is urgently necessary to develop convenient, reliable, ultrasensitive and specific methods of ochratoxin A determination in food safety owing to its high toxicity. In the present study, an ultrasensitive and labeled-free fluorescent aptamer sensor combining real-time fluorescence with strand displacement amplification (SDA) was fabricated for the determination of OTA. In the presence of OTA, the OTA–aptamer combines with OTA, thus opening hairpins. Then, SDA primers specifically bind to the hairpin stem, which is used for subsequent amplification as a template. SDA amplification is initiated under the action of Bst DNA polymerase and nicking endonuclease. The amplified products (ssDNA) are dyed with SYBR Green II and detected with real-time fluorescence. The method has good linearity in the range of 0.01–50 ng mL−1, with the lowest limit of detection of 0.01 ng mL−1. Additionally, the fluorescent aptamer sensor shows outstanding specificity and reproducibility. Furthermore, the sensor shows excellent analytical performance in the artificial labeled detection of wheat and oat samples, with a recovery rate of 96.1~100%. The results suggest that the developed sensor has a promising potential application for the ultrasensitive detection of contaminants in food. Full article
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Review

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24 pages, 3394 KiB  
Review
Occurrence and Chemistry of Tropane Alkaloids in Foods, with a Focus on Sample Analysis Methods: A Review on Recent Trends and Technological Advances
by Lorena González-Gómez, Sonia Morante-Zarcero, Damián Pérez-Quintanilla and Isabel Sierra
Foods 2022, 11(3), 407; https://0-doi-org.brum.beds.ac.uk/10.3390/foods11030407 - 30 Jan 2022
Cited by 31 | Viewed by 5333
Abstract
Tropane alkaloids (TAs) are natural toxins produced by different plants, mainly from the Solanaceae family. The interest in TAs analysis is due to the serious cases of poisoning that are produced due to the presence of TA-producing plants in a variety of foods. [...] Read more.
Tropane alkaloids (TAs) are natural toxins produced by different plants, mainly from the Solanaceae family. The interest in TAs analysis is due to the serious cases of poisoning that are produced due to the presence of TA-producing plants in a variety of foods. For this reason, in recent years, different analytical methods have been reported for their control. However, the complexity of the matrices makes the sample preparation a critical step for this task. Therefore, this review has focused on (a) collecting the available data in relation to the occurrence of TAs in foods for human consumption and (b) providing the state of the art in food sample preparation (from 2015 to today). Regarding the different food categories, cereals and related products and teas and herbal teas have been the most analyzed. Solid–liquid extraction is still the technique most widely used for sample preparation, although other extraction and purification techniques such as solid-phase extraction or QuEChERS procedure, based on the use of sorbents for extract or clean-up step, are being applied since they allow cleaner extracts. On the other hand, new materials (molecularly imprinted polymers, mesostructured silica-based materials, metal–organic frameworks) are emerging as sorbents to develop effective extraction and purification methods that allow lower limits and matrix effects, being a future trend for the analysis of TAs. Full article
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