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Gels
Special Issues
Gels in Medicine and Surgery
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Gels in Medicine and Surgery

A special issue of Gels (ISSN 2310-2861).

Deadline for manuscript submissions: closed (31 March 2021) | Viewed by 6900

Special Issue Editors

Dr. Luca Fiorillo

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Guest Editor
Department of Biomedical and Dental Sciences, Morphological and Functional Images, University of Messina, Policlinico G. Martino, Via, Consolare Valeria, 98100 Me, Italy
Interests: oral biology; odontogenesis; periodontitis; oral biofilm; wound healing; biomaterials; biocompatibility; titanium surface; enamel; tissue regeneration
Special Issues, Collections and Topics in MDPI journals
Dr. Giovanni Luca Romano

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Guest Editor
Department of Biomedical and Biotechnological Sciences (BIOMETEC), Section of Pharmacology, University of Catania, 95124 Catania, Italy
Interests: the study of ocular pharmacology with a specific focus on therapies for neurodegenerative diseases affecting the retina and optic nerve
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue aims to promote scientific research in the field of gels, particularly in the biomedical field. The topics covered in this Special Issue may concern the use of biomaterials in medicine, surgery in all its facets (from regenerative to healing management), clinical studies, protocols, new proposals on pharmaceutical formulations and bioengineering studies and on the behavior of the latter. Furthermore, in regenerative surgery, it is necessary to report the growth factors and all the biomaterials that are used. With this Special Issue, we aim to promote new biomaterials in the biomedical field. Gels in the pharmacological, biomaterials, or even regenerative surgery fields are increasingly widespread. An important component (as opposed to the evolution in the medical field of gel materials) is represented by all those materials used for the field of aesthetic surgery. These, as well as being used in cosmetic surgery, could be used in general surgery, such as antibiotic gels, in maxillofacial surgery as a disinfectant gel, or even in dentistry as an etching gel or whitener. This Special Issue, therefore, aims to promote the dissemination and knowledge of all biomedical materials used in the therapeutic field.

Dr. Luca Fiorillo
Dr. Giovanni Luca Romano
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Gels is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomedical materials
  • surgery
  • disinfectant and antimicrobial gels
  • wound healing
  • plastic surgery
  • cosmetic
  • pharmaceutics
  • biomaterials and bioengineering

Published Papers (2 papers)

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Editorial

Jump to: Research

4 pages, 205 KiB  
Editorial
Gels in Medicine and Surgery: Current Trends and Future Perspectives
by Luca Fiorillo and Giovanni Luca Romano
Gels 2020, 6(4), 48; https://0-doi-org.brum.beds.ac.uk/10.3390/gels6040048 - 03 Dec 2020
Cited by 10 | Viewed by 2600
Abstract
Gel is a two-phase elastic colloidal material, consisting of a dispersed liquid incorporated in the solid phase [...] Full article
(This article belongs to the Special Issue Gels in Medicine and Surgery)

Research

Jump to: Editorial

20 pages, 2736 KiB  
Article
Topical Mucoadhesive Alginate-Based Hydrogel Loading Ketorolac for Pain Management after Pharmacotherapy, Ablation, or Surgical Removal in Condyloma Acuminata
by Salima El Moussaoui, Francisco Fernández-Campos, Cristina Alonso, David Limón, Lyda Halbaut, Maria Luisa Garduño-Ramirez, Ana Cristina Calpena and Mireia Mallandrich
Gels 2021, 7(1), 8; https://0-doi-org.brum.beds.ac.uk/10.3390/gels7010008 - 23 Jan 2021
Cited by 18 | Viewed by 3530
Abstract
Condyloma acuminata is an infectious disease caused by the human papilloma virus (HPV) and one of the most common sexually transmitted infections. It is manifested as warts that frequently cause pain, pruritus, burning, and occasional bleeding. Treatment (physical, chemical, or surgical) can result [...] Read more.
Condyloma acuminata is an infectious disease caused by the human papilloma virus (HPV) and one of the most common sexually transmitted infections. It is manifested as warts that frequently cause pain, pruritus, burning, and occasional bleeding. Treatment (physical, chemical, or surgical) can result in erosion, scars, or ulcers, implying inflammatory processes causing pain. In this work, a biocompatible topical hydrogel containing 2% ketorolac tromethamine was developed to manage the painful inflammatory processes occurring upon the removal of anogenital condylomas. The hydrogel was physically, mechanically, and morphologically characterized: it showed adequate characteristics for a topical formulation. Up to 73% of ketorolac in the gel can be released following a one-phase exponential model. Upon application on human skin and vaginal mucosa, ketorolac can permeate through both of these and it can be retained within both tissues, particularly on vaginal mucosa. Another advantage is that no systemic side effects should be expected after application of the gel. The hydrogel showed itself to be well tolerated in vivo when applied on humans, and it did not cause any visible irritation. Finally, ketorolac hydrogel showed 53% anti-inflammatory activity, suggesting that it is a stable and suitable formulation for the treatment of inflammatory processes, such as those occurring upon chemical or surgical removal of anogenital warts. Full article
(This article belongs to the Special Issue Gels in Medicine and Surgery)
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