Chromosome-Centric View of the Genome Evolution and Organization

A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Cytogenomics".

Deadline for manuscript submissions: closed (20 June 2022) | Viewed by 3730

Special Issue Editors

Institute of Molecular and Cellular Biology of the Siberian Branch of the Russian Academy of Sciences (IMCB SB RAS), 630090 Novosibirsk, Russia
Interests: evolution of vertebrate genomes; sex determination and sex chromosomes; B chromosomes; comparative genomics
Special Issues, Collections and Topics in MDPI journals
Fralin Life Science Institute, Virginia Tech, Blacksburg, VA, USA
Interests: comparative genomics; cytogenetics; chromosome evolution; population genomics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Chromosomes represent important units of inheritance, recombination, and evolution in all cellular organisms. Thus, our understanding of the genome function and evolution is incomplete without knowledge of its organization at the chromosomal level. Recent advances in genome and chromosome technologies, including long-read sequencing, Hi-C scaffolding, chromosome flow sorting, and physical and optical mapping allow us to obtain genome assemblies at the level of complete chromosomes. Such assemblies provide new opportunities to study chromosome organization and evolution, structural genome variations, gene movements, sex-biased gene expression, epigenomic modifications, and long-range chromatin interactions. This Special Issue is the second edition on the same topic where we would like to invite submissions of original research and review articles with a special focus on chromosomes and our understanding of the genome structure, function, and evolution. Articles on topics ranging from the development of new technologies to comprehensive genome analyses are welcome.

Dr. Vladimir Trifonov
Dr. Maria Sharakhova
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • genome organization
  • genome evolution
  • chromosome
  • chromosome rearrangements
  • chromatin
  • karyotype evolution

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

14 pages, 732 KiB  
Review
Chromosome Changes in Soma and Germ Line: Heritability and Evolutionary Outcome
by Irina Bakloushinskaya
Genes 2022, 13(4), 602; https://0-doi-org.brum.beds.ac.uk/10.3390/genes13040602 - 28 Mar 2022
Cited by 4 | Viewed by 3359
Abstract
The origin and inheritance of chromosome changes provide the essential foundation for natural selection and evolution. The evolutionary fate of chromosome changes depends on the place and time of their emergence and is controlled by checkpoints in mitosis and meiosis. Estimating whether the [...] Read more.
The origin and inheritance of chromosome changes provide the essential foundation for natural selection and evolution. The evolutionary fate of chromosome changes depends on the place and time of their emergence and is controlled by checkpoints in mitosis and meiosis. Estimating whether the altered genome can be passed to subsequent generations should be central when we consider a particular genome rearrangement. Through comparative analysis of chromosome rearrangements in soma and germ line, the potential impact of macromutations such as chromothripsis or chromoplexy appears to be fascinating. What happens with chromosomes during the early development, and which alterations lead to mosaicism are other poorly studied but undoubtedly essential issues. The evolutionary impact can be gained most effectively through chromosome rearrangements arising in male meiosis I and in female meiosis II, which are the last divisions following fertilization. The diversity of genome organization has unique features in distinct animals; the chromosome changes, their internal relations, and some factors safeguarding genome maintenance in generations under natural selection were considered for mammals. Full article
(This article belongs to the Special Issue Chromosome-Centric View of the Genome Evolution and Organization)
Show Figures

Figure 1

Back to TopTop