Special Issue "Genetic Basis of Stress-Related Neuropsychiatric Disorders"

A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Neurogenomics".

Deadline for manuscript submissions: 25 September 2022.

Special Issue Editor

Dr. Dubravka Švob Štrac
E-Mail Website
Guest Editor
Rudjer Boskovic Institute, Division of Molecular Medicine, Laboratory for Molecular Neuropsychiatry, 10000 Zagreb, Croatia
Interests: molecular genetics of psychiatric disorders; genetics in addiction research; pharmacogenetics; neurobiology; neuropharmacology; neurodegenerative diseases

Special Issue Information

Dear Colleagues,

Environmental stressful events in combination with genetic underpinnings might trigger the development of various stress-related neuropsychiatric disorders, including post-traumatic stress disorder, anxiety and mood disorders, substance use disorders, and many others. Acute or chronic exposure to stress can lead to numerous adaptive and maladaptive changes in different brain regions, affecting both neurotransmission and morphology, and represents one of the main risk factors in the etiopathogenesis of neuropsychiatric diseases. However, there are other social and biological factors, including genetic determinants, which differentiate between individuals who will develop neuropsychiatric disorders following stress exposure from those who will be resilient. Therefore, the identification of genetic and epigenetic mechanisms underlying resilience and vulnerability to stress is essential in order to better understand the pathophysiology of neuropsychiatric disorders, and for their prevention and treatment. The Special Issue of Genes, “Genetic Basis of Stress-Related Neuropsychiatric Disorders”, will present recent findings on the research targeting genetic background, stress-associated epigenetic changes, as well as gene–stress interactions in different stress-related neuropsychiatric disorders, and give a broad overview of new advances in the field, including pathophysiological mechanisms, model systems, diagnostic biomarkers, and therapeutic approaches.

Dr. Dubravka Švob Štrac
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • psychiatric disorders
  • genetics
  • epigenetics
  • environment
  • stress
  • GxE interaction
  • risk factors
  • polymorphisms
  • gene expression
  • molecular mechanisms
  • biomarkers
  • PTSD
  • mood disorders
  • anxiety disorders
  • substance use disorders
  • addiction
  • human genetics
  • animal models
  • therapeutic targets

Published Papers

This special issue is now open for submission.
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