Special Issue "Microbial Extracellular Vesicles"
Deadline for manuscript submissions: 1 November 2021.
Interests: molecular microbiology; horizontal gene transfer; DNA conjugation; extracellular vesicles; virology
It has only been 20 years since microbiologists realized the significance of the production of extracellular vesicles (EVs) by bacteria and archaea. This widespread phenomenon has not only been observed under laboratory growth conditions but also in environmental conditions as in seawater, biofilm formations, or during infections, underscoring the importance of EVs to various biological processes. The recent discovery of long tubular structures termed “nanotubes”, emerging from the cell wall and composed of EVs chains or consecutive constricted segments, suggests a connected process between EVs production and nanotubes formation. The heterogeneity of microbial EVs is impressive, with some species producing EVs harbouring proteins (especially enzymes and toxins), signal molecules, but also nucleic acids such as RNA and DNA. Interestingly, the nature of the DNA transported by EVs is not restricted to mobile genetic elements such as plasmids or viruses, but sometimes corresponds to cellular genomic DNA, enabling horizontal transfers between species (a process tentatively called vesiduction). However, in many cases where EVs production is known, the potential transfer of RNA or DNA has not always been tested experimentally. Moreover, very little is known about the genetic determinants promoting or increasing the biogenesis and release of EVs.
This Special Issue of Genes on “Microbial Extracellular Vesicles” will address any original articles leading to a better comprehension of how EVs are released from cells, how the production of EVs is regulated, and the extent to which EVs are involved in genetic exchanges and/or trigger gene regulation in the target cell. General reviews dedicated to microbial EVs will also be welcome.Dr. Nicolas Soler
Dr. Aurore Gorlas
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- extracellular vesicles
- horizontal gene transfer
- microbial genetics
- vesicle release
- gene regulation