Special Issue "Chronic Kidney Disease: The Global Challenge"
A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Health Behavior, Chronic Disease and Health Promotion".
Deadline for manuscript submissions: 31 December 2021.
2. Institute of Health Research-INCLIVA, Valencia, Spain
3. Facultad de Ciencias de la Salud, Health Sciences School, Universidad Cardenal Herrera CEU, Spain
Interests: chronic kidney disease; cardiovascular and diabetic kidney disease; bone mineral metabolism; cardioremal disease
2. Department of Medicine, University of Valencia, Valencia, Spain
Interests: chronic kidney disease; diabitic kidney disease; anemia; cardiorenal disease
Chronic kidney disease is positioned as one of the greatest public health challenges in the following decades due, among other problems, to its high complexity index and the elevated consumption of economic and human resources that it supposes. On the one hand, the rapid growth in the number of diabetic patients encountered in developed countries, derived from sedentary lifestyle and diets rich in carbohydrates, causes a high incidence of diabetic kidney disease, this being the main cause of end stage kidney disease with the need for renal replacement therapies. Moreover, the coexistence of other risk factors of chronic kidney disease such as hypertension and adiposity contributes to the higher cardiovascular morbidity and mortality rates observed in these patients. Beyond the classical cardiovascular risk factors, other factors inherent to kidney disease itself such as alterations in bone mineral metabolism, anemia or electrolyte disorders have been the target of intensive research in recent years. Of note, the inherent link between heart and kidney disease is a matter of intense and fertile debate.
Currently, we are witness to remarkable advances that make us look to the future with optimism. The introduction of drugs such as iSGLT2 or GLP-1, with the ability to slow the progression of kidney damage, together with all the advantages that they provide in the field of cardiovascular disease or the recent advances in the knowledge of the pathophysiology of anemia, and the development of new molecules, such as proline hydroxylase inhibitors, position nephrology at the forefront of the advancement of medicine. Of interest, new evidence supports the safe use of mineralocorticoid receptor antagonists and potassium resins to control proteinuria and hyperpotassemia associated with kidney disease, without of course forgetting the key role of kidney transplantation, which is a primary objective in renal replacement treatment and key to the sustainable maintenance of the system both from a medical and economic point of view.
Dr. María Jesús Puchades
Dr. Luis D' Marco
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- Chronic kidney disease
- Diabetes mellitus
- Diabetic kidney disease
- Cardiorenal syndrome
- Anemia in chronic kidney disease
- Kidney transplantation