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Eye in Diabetes

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Health Behavior, Chronic Disease and Health Promotion".

Deadline for manuscript submissions: closed (31 December 2021) | Viewed by 3893

Special Issue Editor


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Guest Editor
Department of Ophthalmology and Visual Science, Chiba University, Chiba 2608670, Japan
Interests: cornea; keratoconus; keratopathy; neurodegeneration; nutrigenomics

Special Issue Information

Dear Colleagues,

The incidence of diabetes has risen markedly in the past several decades and the complications associated with diabetes are the leading cause of blindness in the working age adults.

Impaired corneal innervation and development of retinopathy in diabetes are important indicators of diabetic neuropathy. Early diagnosis of neuropathy is very important for evaluation of risks and therapeutic management and efforts for the preservation of visual function are our main goal.

This special issue is intended to focus on describing the most recent findings on impaired corneal innervation and retinal changes in diabetic patients, investigations on mechanisms of neuronal cell death and findings in theraputical apporaches for diabetic kerato- and retinopathy.

Potential topics include but are not limited to the following:

-New Insights in Understanding Diabetic Neuropathy

-Anterior segment in diabetes (corneal changes, impaired corneal innervation)

- Early detection of diabetic retinopathy and keratopathy using non-invasive imaging

- Diabetic Retinopathy: Current Concepts and Future Directions

- Novel Therapeutic Targets for Diabetic Retinopathy and Keratopathy

Dr. Guzel Bikbova
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • diabetes
  • keratopathy
  • neurodegeneration

Published Papers (1 paper)

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Review

19 pages, 2368 KiB  
Review
Neurovascular Impairment and Therapeutic Strategies in Diabetic Retinopathy
by Toshiyuki Oshitari
Int. J. Environ. Res. Public Health 2022, 19(1), 439; https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph19010439 - 31 Dec 2021
Cited by 16 | Viewed by 3302
Abstract
Diabetic retinopathy has recently been defined as a highly specific neurovascular complication of diabetes. The chronic progression of the impairment of the interdependence of neurovascular units (NVUs) is associated with the pathogenesis of diabetic retinopathy. The NVUs consist of neurons, glial cells, and [...] Read more.
Diabetic retinopathy has recently been defined as a highly specific neurovascular complication of diabetes. The chronic progression of the impairment of the interdependence of neurovascular units (NVUs) is associated with the pathogenesis of diabetic retinopathy. The NVUs consist of neurons, glial cells, and vascular cells, and the interdependent relationships between these cells are disturbed under diabetic conditions. Clinicians should understand and update the current knowledge of the neurovascular impairments in diabetic retinopathy. Above all, neuronal cell death is an irreversible change, and it is directly related to vision loss in patients with diabetic retinopathy. Thus, neuroprotective and vasoprotective therapies for diabetic retinopathy must be established. Understanding the physiological and pathological interdependence of the NVUs is helpful in establishing neuroprotective and vasoprotective therapies for diabetic retinopathy. This review focuses on the pathogenesis of the neurovascular impairments and introduces possible neurovascular protective therapies for diabetic retinopathy. Full article
(This article belongs to the Special Issue Eye in Diabetes)
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