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Special Issue "Lifestyle, Gender and Cancers"

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Health Behavior, Chronic Disease and Health Promotion".

Deadline for manuscript submissions: closed (31 July 2021).

Special Issue Editors

Dr. Erika Di Zazzo
E-Mail Website1 Website2
Guest Editor
Department of Medicine and Health Science, University of Molise, 86100 Campobasso, Italy
Interests: cancers; PRDM genes; steroid receptors; signal transduction
Special Issues and Collections in MDPI journals
Dr. Monica Rienzo
E-Mail Website
Guest Editor
Prof. Dr. Ciro Abbondanza
E-Mail Website
Guest Editor
Department of Precision Medicine, University of Campania “Luigi Vanvitelli”, Via L. De Crecchio, 80138 Naples, Italy
Interests: cancers; PRDM genes; steroid receptors
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Cancer represents the second leading cause of mortality, and its incidence is steadily increasing worldwide. Both genetic background and modifiable environmental/lifestyle factors account for cancer etiology. Among them, overweight/obesity, junk food intake, and physical inactivity play a pivotal role.

Moreover, gender is recognized as a major factor controlling incidence, therapeutic responses, and mortality of several cancers. We invite authors to submit both original research articles and review articles that cover recent research advances in the understanding of the links between life style, gender, and cancers.

Dr. Erika Di Zazzo
Dr. Monica Rienzo
Prof. Dr. Ciro Abbondanza
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2300 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Lifestyle
  • Obesity
  • Cancer
  • Gender
  • Sex
  • Diet
  • Physical activity
  • Hormones
  • Cancer risk factor

Published Papers (4 papers)

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Research

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Article
Sun Exposure during Water Sports: Do Elite Athletes Adequately Protect Their Skin against Skin Cancer?
Int. J. Environ. Res. Public Health 2021, 18(2), 800; https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph18020800 - 19 Jan 2021
Viewed by 897
Abstract
Excessive sun exposure is the main avoidable cause of skin cancer. Outdoor sports performed without adequate photoprotection are risky practices in this respect. This study examines whether elite athletes in water sports (specifically surfing, windsurfing, and sailing) take appropriate measures to protect their [...] Read more.
Excessive sun exposure is the main avoidable cause of skin cancer. Outdoor sports performed without adequate photoprotection are risky practices in this respect. This study examines whether elite athletes in water sports (specifically surfing, windsurfing, and sailing) take appropriate measures to protect their skin from the sun, and whether there are differences in this respect according to age, gender, or sports discipline. This study is based on a questionnaire-based health survey. World championship competitors completed a self-administered questionnaire on their sun protection and exposure habits, as well as sunburns during the last sports season. In total, 246 participants, with an age range of 16–30 years, completed the questionnaire. Of these, 49.6% used inadequate sun protection. Those who protected their skin appropriately tended to be older than those who did not (average age = 23.28 and 20.69 years, respectively; p = 0.000). There were no significant differences in sun protection habits between male and female athletes. The rate of sunburn was very high (76.7%). A high proportion (22.5%) of participants never used sunscreen. Elite athletes in water sports are at real risk of skin lesions from overexposure to the sun, associated with inadequate photoprotection practices. Campaigns to raise awareness and to promote the early detection of skin cancer should target these risk groups. Full article
(This article belongs to the Special Issue Lifestyle, Gender and Cancers)

Review

Jump to: Research, Other

Review
Relationship Dynamics among Couples Dealing with Breast Cancer: A Systematic Review
Int. J. Environ. Res. Public Health 2021, 18(14), 7288; https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph18147288 - 07 Jul 2021
Viewed by 513
Abstract
Most studies have been concerned with the experiences and needs of women with breast cancer and spouses/partners separately. In this review, the relationship dynamics that characterize the couple’s experience of breast cancer treatment were investigated. Findings will inform both researchers and professionals in [...] Read more.
Most studies have been concerned with the experiences and needs of women with breast cancer and spouses/partners separately. In this review, the relationship dynamics that characterize the couple’s experience of breast cancer treatment were investigated. Findings will inform both researchers and professionals in the area of oncology. A systematic literature search was performed in CINAHL, PsychINFO, MEDLINE, Scopus and Web of Science. A checklist for qualitative and observational studies was used to evaluate the methodological quality of the studies. Seventeen studies were included, and the synthesis of the literature revealed five domains that characterized the dyadic process: dyadic coping strategies, psychosocial support, communication, the couple’s sexual life and spirituality. The included studies provide the basis for knowledge and awareness about the experience of couples with cancer, the specific dimensions enacted during the breast cancer treatment path and the type of responses that are associated with a positive couple’s adjustment to the disease. Full article
(This article belongs to the Special Issue Lifestyle, Gender and Cancers)
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Review
Food, Nutrition, Physical Activity and Microbiota: Which Impact on Lung Cancer?
Int. J. Environ. Res. Public Health 2021, 18(5), 2399; https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph18052399 - 01 Mar 2021
Viewed by 1104
Abstract
Lung cancer still represents the leading cause of cancer-related death, globally. Likewise, malnutrition and inactivity represent a major risk for loss of functional pulmonary capacities influencing overall lung cancer severity. Therefore, the adhesion to an appropriate health lifestyle is crucial in the management [...] Read more.
Lung cancer still represents the leading cause of cancer-related death, globally. Likewise, malnutrition and inactivity represent a major risk for loss of functional pulmonary capacities influencing overall lung cancer severity. Therefore, the adhesion to an appropriate health lifestyle is crucial in the management of lung cancer patients despite the subtype of cancer. This review aims to summarize the available knowledge about dietary approaches as well as physical activity as the major factors that decrease the risk towards lung cancer, and improve the response to therapies. We discuss the most significant dietary schemes positively associated to body composition and prognosis of lung cancer and the main molecular processes regulated by specific diet schemes, functional foods and physical activity, i.e., inflammation and oxidative stress. Finally, we report evidence demonstrating that dysbiosis of lung and/or gut microbiome, as well as their interconnection (the gut–lung axis), are strictly related to dietary patterns and regular physical activity playing a key role in lung cancer formation and progression, opening to the avenue of modulating the microbiome as coadjuvant therapy. Altogether, the evidence reported in this review highlights the necessity to consider non-pharmacological interventions (nutrition and physical activity) as effective adjunctive strategies in the management of lung cancer. Full article
(This article belongs to the Special Issue Lifestyle, Gender and Cancers)
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Other

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Systematic Review
Gender-Dependent Specificities in Cutaneous Melanoma Predisposition, Risk Factors, Somatic Mutations, Prognostic and Predictive Factors: A Systematic Review
Int. J. Environ. Res. Public Health 2021, 18(15), 7945; https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph18157945 - 27 Jul 2021
Viewed by 264
Abstract
Background and aim: Over the last decades, the incidence of melanoma has been steadily growing, with 4.2% of the population worldwide affected by cutaneous melanoma (CM) in 2020 and with a higher incidence and mortality in men than in women. We investigated both [...] Read more.
Background and aim: Over the last decades, the incidence of melanoma has been steadily growing, with 4.2% of the population worldwide affected by cutaneous melanoma (CM) in 2020 and with a higher incidence and mortality in men than in women. We investigated both the risk factors for CM development and the prognostic and predictive factors for survival, stratifying for both sex and gender. Methods: We conducted a systematic review of studies indexed in PUB-MED, EMBASE, and Scopus until 4 February 2021. We included reviews, meta-analyses, and pooled analyses investigating differences between women and men in CM risk factors and in prognostic and predictive factors for CM survival. Data synthesis: Twenty-four studies were included, and relevant data extracted. Of these, 13 studies concerned potential risk factors, six concerned predictive factors, and five addressed prognostic factors of melanoma. Discussion: The systematic review revealed no significant differences in genetic predisposition to CM between males and females, while there appear to be several gender disparities regarding CM risk factors, partly attributable to different lifestyles and behavioral habits between men and women. There is currently no clear evidence of whether the mutational landscapes of CM differ by sex/gender. Prognosis is justified by a complex combination of phenotypes and immune functions, while reported differences between genders in predicting the effectiveness of new treatments are inconsistent. Overall, the results emerging from the literature reveal the importance of considering the sex/gender variable in all studies and pave the way for including it towards precision medicine. Conclusions: Men and women differ genetically, biologically, and by social construct. Our systematic review shows that, although fundamental, the variable sex/gender is not among the ones collected and analyzed. Full article
(This article belongs to the Special Issue Lifestyle, Gender and Cancers)
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