Special Issue "Neuro-Immune Interactions in Autism Spectrum Disorders"
A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Health Behavior, Chronic Disease and Health Promotion".
Deadline for manuscript submissions: 30 September 2021.
Interests: autism spectrum disorder; inflammation, fever; interleukins; acetaminophen use; endocannabinoid system; cannabidiol; neuro-immune activation
Interests: autism; stem cells; gene expression; neuro-immunology
Special Issues and Collections in MDPI journals
Special Issue in International Journal of Environmental Research and Public Health: Environmental Exposures and Autism Spectrum Disorders
Special Issue in Behavioral Sciences: Behavioral Disorders, Coronavirus and the Nervous System
Special Issue Introduction: Maternal immune activation and early life infections are factors that can increase risk of autism and related developmental disorders. Given this, it follows that treatments which modulate the immune response, either systemically or in the brain, may hold promise for management or amelioration of autism symptoms. This Special Issue on neuro-immune interactions in autism seeks to provide a timely update on both fronts and seeks research contributions of both pre-clinical and clinical findings, as well as reviews on specific topics within this scope.
Autism spectrum disorder is changing the lives of tens of thousands of children around the world, and there has recently been a growing realization that it can be brought on by neuro-inflammation which can occur in the prenatal and the early postnatal period. This inflammation can induce subtle changes in brain anatomy and functioning which can be difficult to recognize and even more difficult to treat. Some of these changes in the brain are seen by decreased number of neurons, shortened axons, and problems with myelinization in individuals with ASD. We have posited that the contributing factors for these changes come from neuro-immune interactions evidenced by changes in amounts and types of interleukins, cytokines, and immunoglobulins. Currently, there is no effective medication to treat the core symptoms of ASD. The endocannabinoid system can control inflammation through receptors on immune system cells. Research has shown that cannabidiol which affects these receptors holds promise as a possible treatment. Papers addressing these and other topics exploring neuro-immune interactions in ASD are invited for this Special Issue, especially those with new ideas for treatment and prevention of this as yet incurable disorder.
Dr. Stephen Schultz
Dr. Dario Siniscalco
Dr. Georgianna G. Gould
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2300 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Immune activation
- Immune response
- Social behavior deficits, Perinatal infections
- Cannabinoids, Autism spectrum disorders