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New Biomarkers and Diagnostics in Oral Cancer and Oral Diseases

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Global Health".

Deadline for manuscript submissions: closed (31 December 2021) | Viewed by 8359

Special Issue Editor


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Guest Editor
Department of General Surgery and Surgical-Medical Specialties, University of Catania, 95124 Catania, Italy
Interests: periodontitis; oral surgery; oral pathology; oral health-systemic health; bone biology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Oral health is essential to general health and well-being at every stage of life. A healthy mouth enables not only nutrition of the physical body, but also enhances social interaction and promotes self-esteem and feelings of well-being. The mouth serves as a “window” to the rest of the body, providing signals of general health disorders. Oral and periodontal conditions have an impact on overall health and disease. Bacteria from the mouth can cause infection in other parts of the body when the immune system has been compromised by disease or medical treatments (e.g., infective endocarditis). Systemic conditions and their treatment are also known to impact on oral health (e.g., reduced saliva flow, altered  balance of oral microorganisms).
The aim of this Special Issue is to provide insight into the recent advances in the field of oral cancer and oral diseases. Potential topics in this Special Issue include, but are not limited to, in-vitro and clinical research on oral cancers and oral diseases, and on the biomaterials involved in the oral health manteinance.
Studies incorporating a new approach or providing novel information are of higher priority. Systematic and narrative reviews in the field of dentistry mainly on infectious disease are also welcome.

It is our pleasure to invite you to contribute to this Special Issue.

Prof. Dr. Gaetano Isola
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Oral health
  • oral microbiology
  • oral bacteria
  • oral diseases
  • periodontal diseases
  • peri-implant diseases
  • dental infections
  • oral surgery
  • oral pathology
  • dental biomaterials
  • in-vitro research
  • clinical research

Published Papers (3 papers)

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Editorial

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3 pages, 240 KiB  
Editorial
Early Biomarkers of Periodontitis: New Challenges for a Personalized Medicine Approach
by Gaetano Isola
Int. J. Environ. Res. Public Health 2022, 19(1), 251; https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph19010251 - 27 Dec 2021
Cited by 2 | Viewed by 2601
Abstract
Recently, the concept of precision medicine has attracted attention [...] Full article
(This article belongs to the Special Issue New Biomarkers and Diagnostics in Oral Cancer and Oral Diseases)
3 pages, 260 KiB  
Editorial
Advances in Biomarkers and Diagnostics in Periodontitis and Oral Diseases
by Gaetano Isola
Int. J. Environ. Res. Public Health 2021, 18(4), 1886; https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph18041886 - 15 Feb 2021
Cited by 8 | Viewed by 2732
Abstract
Oral health is essential to general health and well-being at every stage of life [...] Full article
(This article belongs to the Special Issue New Biomarkers and Diagnostics in Oral Cancer and Oral Diseases)

Research

Jump to: Editorial

12 pages, 3720 KiB  
Article
IL-17F Gene rs763780 and IL-17A rs2275913 Polymorphisms in Patients with Periodontitis
by Małgorzata Mazurek-Mochol, Małgorzata Kozak, Damian Malinowski, Krzysztof Safranow and Andrzej Pawlik
Int. J. Environ. Res. Public Health 2021, 18(3), 1081; https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph18031081 - 26 Jan 2021
Cited by 9 | Viewed by 2215
Abstract
Background: Periodontitis (PD) is a chronic inflammatory disease that can eventually lead to tooth loss. Genetic and environmental factors such as smoking are involved in the pathogenesis of PD. The development of PD is potentiated by various pathogens that induce an immune [...] Read more.
Background: Periodontitis (PD) is a chronic inflammatory disease that can eventually lead to tooth loss. Genetic and environmental factors such as smoking are involved in the pathogenesis of PD. The development of PD is potentiated by various pathogens that induce an immune response leading to the production of cytokines, such as interleukin (IL)-17. The synthesis of IL-17 is influenced genetically. The polymorphisms in IL-17 gene may affect the synthesis of IL-17. The aim of this study was to examine the association between the IL-17F rs763780 and IL-17A rs2275913 polymorphisms and PD in non-smoking and smoking patients to check if these polymorphisms could be a risk factor for PD. Methods: The study enrolled 200 patients with PD (130 non-smokers and 70 smokers) and 160 control subjects (126 non-smokers and 34 smokers). Periodontitis was diagnosed on the basis of 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. All samples were genotyped using allelic discrimination assays with TaqMan® probes on a Real-Time PCR Detection System. Results: There were no statistically significant differences in the distribution of the IL-17F rs763780 and IL-17A rs2275913 genotypes and alleles between patients with PD and control subjects, between smoking patients with PD and smoking control subjects, and between non-smoking patients with PD and non-smoking control subjects. Conclusions: The results of this study suggest a lack of statistically significant associations between IL-17F rs763780 and IL-17A rs2275913 polymorphisms and PD in Polish population. Full article
(This article belongs to the Special Issue New Biomarkers and Diagnostics in Oral Cancer and Oral Diseases)
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