Special Issue "Thyroid Cancer Management"
A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Health Behavior, Chronic Disease and Health Promotion".
Deadline for manuscript submissions: 31 August 2021.
Interests: management of thyroid carcinoma; radioiodine therapy; radiation induced thyroid cancer; screening; environmental risk factors; prevention, second malignancy
Interests: radiation induced thyroid cancer; screening; environmental risk factors; nitrate metabolism and other endocrine disruptors; prevention, minimally invasive therapy; second malignancy
An increase in thyroid cancer incidence since the late 80’s in many developed countries is higher than in any other cancer. Many studies have demonstrated that screening with ultrasonography is an important factor contributing to this rise. The increase of thyroid cancer incidence however may not be completely dependent on screening only. It has to be reviewed that the exposure to known and unknown risk factors like radiation, lifestyle changes, and environmental pollutants contribute to the increase of thyroid cancer incidence.
In last decade, new approaches like minimally invasive therapy (radiofrequency ablation (RFA, laser ablation), or new strategies for active surveillance of early stages of thyroid cancer are developing and helping to avoid overtreatment and surgical complications. It is very important to understand the risk factors for the mechanisms of development of secondary primary malignancies, to assess the effect of radioiodine therapy on the possibility of secondary cancer induction and complications such as impaired fertility.
For primary prevention of thyroid cancer, it is very important to refer the patient for a radiological examination only if the strict indication is justified according to the International Committee for Radiological Protection. In clinical practice, it is also important to take into account and minimize other risk factors: prevention of obesity and weight reduction, adequate treatment of various thyroid diseases, avoidance of excessive consumption of nitrates and other endocrine disruptors/environmental pollutants. More research is also required to identify other reasons of the increasing incidence and predictors of aggressive vs indolent behavior of thyroid cancer to avoid unnecessary screening activity, overdiagnosis, and overtreatment
Prof. Dr. Valentina Drozd
Prof. Dr. Christoph Reiners
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- thyroid cancer management
- epidemiology/risk factors
- screening/early diagnosis
- surgical approach/radioiodine therapy
- outcome/side effects