Advances in Alzheimer’s Disease and Healthy Aging
A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Aging".
Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 3035
Special Issue Editors
Interests: neuroscience; behavior; aging; neurodegeneration; Alzheimer’s disease; epigenetics; mice; C. elegans; bioinformatics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Age-related cognitive decline—especially memory impairment—is one of the most prevalent consequences of growing older. The severity of age-related cognitive decline predisposes to neurodegenerative diseases like Alzheimer’s disease (AD). The molecular mechanisms of age-related cognitive decline and AD are considered to be multifactorial, and implicate the interaction of genetics and environmental factors (nutrition and pollutants, among others), acting as susceptibility factors or triggers that promote brain injury accumulation due to their chronicity during aging.
Although the main neuropathological hallmarks such as amyloid plaques and tau pathology are well-described, the causes of AD remain unknown, and no preventive or curative treatments are available. The treatments are currently divided into acetylcholinesterase inhibitors (AChEIs), and an antagonist of the N-methyl-D-aspartic (NMDA) receptor. Nevertheless, those drugs can only relieve symptoms for a short time, and cannot delay the progression of AD. Recent failures and the limited therapeutics in phase III suggest that it is time to consider new and alternative AD treatment strategies.
Thus, this Special Issue seeks to gather high-quality original research papers and review articles addressing recent advances focused on AD treatments that influence aging through pharmacological or non-pharmacological interventions (environmental enrichment (EE), exercise, meditation, yoga, etc.) and will focus on new insights into cellular, molecular, and cognitive changes that underlie healthy aging and/or the progression of AD pathology.
Dr. Christian Griñán-Ferré
Dr. Verónica Palomera-Avalos
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- aging
- cognitive decline
- Alzheimer’s disease
- neurodegeneration
- drug discovery
- non-pharmacological interventions
- pharmacological interventions
- neuroscience
