Special Issue "Amino Acid Transporters and Signaling in Cancer"
Deadline for manuscript submissions: closed (30 June 2021).
Interests: amino acid transporters; cancer; glutamine metabolism
Metabolic reprogramming in cancer is recognized as a common and integral component of multistep tumorigenesis. Among nutrients, amino acids are central to growth signaling and cellular stress responses; likewise, the cellular machinery involved in delivering and sustaining the amino acid ecosystem is often altered in the course of cancer metabolic reprogramming. As such, amino acid transporters, metabolic enzymes, and signaling proteins are actively investigated as potential targets for cancer therapies. This Special Issue of the International Journal of Molecular Sciences focuses on the role of amino acid transporters and linked signaling proteins involved in cell-autonomous cancer growth and tumorigenesis. Papers are sought particularly in the area of transporter targeting and its effects on metabolism, growth, and stress response signaling in cancer cells and the tumors that they spawn. This rapidly emerging area of research is poised to be an integral component of advances in cancer therapy either directly, or as an adjuvant, as we move into the 2020s.
Dr. Barrie P. Bode
Dr. Neetika Khurana
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Amino acid transporter
- Integrated stress response
- Oxidative stress
- Cell growth