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Special Issue "From Basic Radiobiology to Translational Radiotherapy"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Toxicology".

Deadline for manuscript submissions: 31 January 2022.

Special Issue Editors

Dr. Takamitsu Kato
E-Mail Website
Guest Editor
Department of Environmental & Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA
Interests: DNA damage; flavonoids; DNA repair; cytogenetics; radiobiology
Special Issues and Collections in MDPI journals
Dr. Hiroto Yoshikawa
E-Mail Website
Guest Editor
Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA
Interests: radiation biology; radiation physics; cancer biology

Special Issue Information

Dear Colleagues,

A major goal of radiotherapy is to control tumor mass with minimal effects on the surrounding normal tissues. To achieve this, basic radiation responses in normal and cancer cells need to be understood. In cell molecular biology, this includes DNA damage and repair, cell cycle effects, cell death, and genomic instability, including somatic mutations and epigenetic modifications. Cellular radiation responses are altered by oxygen concentrations, temperature, and other microenvironmental factors, as well as small molecules classified as radio-sensitizers and radio-protectors. Radiotherapy can be combined with other cancer treatment modalities such as chemotherapy and immunotherapy.
This Special Issue is focused on radiobiology research that can be translational to clinical radiotherapy. It includes topics from basic cell and molecular responses to radiation to clinical trials. This Special Issue will help basic radiation and cancer biology researchers as well as clinical radiation oncologists to update their knowledge for better radiotherapy.

Dr. Takamitsu Kato
Dr. Hiroto Yoshikawa
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • ionizing radiation
  • DNA damage
  • DNA repair
  • chromosome aberrations
  • cell death
  • mutations
  • epigenetics
  • hypoxia
  • radiosensitizer
  • radioprotector
  • immunotherapy
  • tumor microenvironment
  • radiotherapy

Published Papers

This special issue is now open for submission.
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