Special Issue "Common Chronic Diseases: Gap for the Treatment"
Deadline for manuscript submissions: 30 June 2021.
2. Academy of Medical Science, Street Tsyurupa 3, Moscow, 117418, Russia; Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, Moscow Region, 142432, Russia
3. GALLY International Research Institute, 7733 Louis Pasteur Drive, #330, San Antonio, TX, 78229, USA
Interests: Normal Physiological Aging; Pharmacogenomics; Mitochondrial Genomics; Mitochondrion and Oxidative stress; Aging and Age-Associated Diseases; diagnosis and treatment of PTSD, Bioamines, Infertilities, Pathophysiology; Alternate treatment options
Recent evidence has associated the aberrant, proximal re-expression of various cell cycle control elements with physiological homestasis, tumor, and metabolic disease-exposed cellular compartment as well as neuronal cell vulnerability in cancer, metabolic disorders (Diabetes), Alzheimer's and Parkinson's diseases, as common chronic diseases. This phenomenon associated with oncogenic transduction pathway activation has attracted the interest of scientists all over the world for a few years now. The role of mast cells (MCs) are main suppliers of bioamines (serotonin, catecholamines, and histamine) in uterus as well as in the brain appeared to be one of the key components regarding maintenance of normal cellular and organ homestasis. Therefore future projects determining the concentration and distribution of bioamines such as histamine, serotonin, and catecholamines in the endometrium and myometrium during the postpartum uterine involution would not only provide their role in the context of the physiological processes but also would open new windows to better understand the pathobiology of cancer and neurodegenerative diseases. The purpose of this Special Issue is to outline areas of research related to neurogenic and oncogenic factors or medicines in the context of potential applications for future treatment of the above mentioned chronic and, largely, incurable diseases.
Prof. Dr. Gjumrakch Aliev
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- chronic inflammation
- oxidative stress
- neurodegenerative diseases
- Alzheimer disease
- Parkinson disease
- diseases triggering pathway
- biogenic amines
- normal physiological process
- brain axis
- mast cells
- extra-organic complex of bioamines supply