Special Issue "Molecular Mechanisms Underlying CNS Inflammation"
Deadline for manuscript submissions: closed (31 May 2021).
The immune system underlies the pathology of many neurological diseases but is also instrumental for the resolution of inflammation and induction of repair. The trigger for activation of the immune system in these diseases may be derived from within the central nervous system (CNS), as seen in, e.g., Alzheimer’s disease or CNS trauma, or systemic immune cell activation may lead to the onset of CNS disease, as is assumed in, e.g., autoimmune diseases such as multiple sclerosis or neuromyelitis optica. Recently, it has become clear that immune mediators also have a key role in resolving inflammatory responses and are crucial for inducing CNS repair. The suppression of detrimental immune responses and the stimulation of beneficial immune responses are considered promising strategies to halt the progression of neurological disease. However, we have just started to comprehend the complex regulation of immune cell function and its interaction with resident brain cells and other body systems such as metabolic pathways, the endocrine system, diet, the microbiome, and the cardiovascular system. Elucidating the molecular mechanisms that regulate the immune system in CNS diseases is key for our understanding of the disease pathology and the development of novel, more effective treatments.
Prof. Dr. Jerome Hendriks
Dr. Jeroen Bogie
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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- Central nervous system
- Immune system
- Neurological disease
- CNS repair