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Special Issue "Molecular Mechanisms of Pathogenesis, Prevention, and Therapy of COVID-19: Summarizing the Results of 2021"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".

Deadline for manuscript submissions: 31 December 2021.

Special Issue Editor

Prof. Dr. Evgenii Gusev
E-Mail Website
Guest Editor
Institute of Immunology and Physiology of the Ural Branch of the Russian Academy of Sciences (IIP UB RAS), Laboratory for immunology of inflammation, Ekaterinburg, Russia
Interests: immunology of inflammation; systemic inflammation; typical pathological processes

Special Issue Information

Dear Colleagues,

COVID-19 as a global public health challenge will eventually go down in history. However, the doors for a potential new generation of CoV infections, as well global epidemics of a different etiological nature, will remain open and that will lead to severe social consequences.

Thus, the time has come for preliminary analysis and generalization of the lessons learned from SARS-CoV-2.

Firstly, this concerns the separation of the unique and distinctive mechanisms of SARS-CoV-2 invasion from the general patterns of the infectious processes and the development of critical complications. The latter concerns the characteristics of not only the general molecular mechanisms of various pathologies but also the integral laws of pathology (models of pathological systems). We will inevitably face the consequences whether these issues are resolved.

Secondly, this applies to general strategies of viral invasions, targeted suppression of infectious agent infects via mechanisms of innate and adaptive host immunity, and the reorientation of these mechanisms against the organism during the development of systemic inflammation.

Thus, it is advisable to reconsider the data of both applied and general principles of pathogenetic therapy, to systematize the analysis of genetic and environmental risk factors for CoV infections, and the role of comorbid diseases in them.

We hope that the planned special issue "Molecular mechanisms of pathogenesis, prevention, and therapy of COVID-19: results of 2021" will be a significant step towards solving these pressing problems.

Prof. Dr. Evgenii Gusev
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • COVID-19
  • SARS-CoV-2
  • pathogenesis
  • inflammation
  • typical pathological processes

Published Papers

This special issue is now open for submission.
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