Journal Browser

Journal Browser

Special Issue "Cytotoxicity on Pharmaceutical Interactions in Chemotherapy"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Toxicology".

Deadline for manuscript submissions: 31 January 2022.

Special Issue Editor

Prof. Dr. Yoshihiro Uesawa
E-Mail Website
Guest Editor
Faculty of Pharmacy, Department of Medical Molecular Informatics, Meiji Pharmaceutical University, Tokyo, Japan
Interests: computational toxicology; chemo/bioinformatics; drug metabolism; drug adverse effect; machine learning; drug interaction; database analysis

Special Issue Information

Dear Colleagues,

A wide variety of anticancer drugs are used for chemotherapy depending on the type of cancer. Many of these anticancer agents have cytotoxic effects on tumor cells as a major mechanism for their anticancer effects. However, insufficient tumor cell selectivity may result in a risk of comorbid side effects, including hematotoxicity due to myelosuppression. Because chemotherapy is often achieved using a combination of drugs, the relationship between these antitumor effects and side effects and anticancer drugs is complex.

The purpose of this Special Issue is to integrate knowledge, including mechanisms of clinically and biochemically useful expression of pharmacological interactions. In other words, it is expected that findings relevant to this topic will be based on the results of biochemical studies through in vivo and in vitro experiments and data accumulated in a variety of clinical studies, including database studies. This combined knowledge allows molecular interpretations of chemotherapy and may contribute to improved clinical outcomes of anticancer therapy.

Prof. Dr. Yoshihiro Uesawa
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • tumor specificity
  • PK/PD interaction
  • adverse effect
  • anticancer drug
  • cytotoxicity
  • chemotherapy
  • cell signaling
  • molecular mechanisms
  • translational research

Published Papers

This special issue is now open for submission.
Back to TopTop