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Special Issue "Cannabinoids and Contractile Function"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: closed (30 September 2021).

Special Issue Editor

Prof. Dr. Lori A. Walker
E-Mail Website
Guest Editor
Deptartment of Medicine/Cardiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA
Interests: Heart failure; Cardiac muscle contractility; Vascular muscle reactivity; Cannabinoids; Cell signaling; Protein Modification; Hypertension

Special Issue Information

Dear Colleagues,

As legislation is rapidly changing across the United States and the world, cannabis use is increasing, both medicinally and recreationally. However, with the increase in use, there has been an increase in reports of adverse cardiovascular outcomes following cannabis use. Since the discovery of tetrahydrocannabinol and cannabidiol (the two major cannabinoids in the cannabis plant) nearly six decades ago, there has been a vast effort to delineate the signaling pathways evoked by cannabinoids in the cannabis plant. In the early 1980s, the first cannabinoid receptor was discovered, and shortly thereafter, the first endogenous cannabinoid receptor ligand was described. Since then, there has been an increasing effort aimed at understanding the mechanism and role of endocannabinoid signaling in health and disease, as well as understanding the effects of exogenous cannabinoid signaling. However, such efforts have been significantly hampered by restrictive legislation, and there is still no consensus on whether cannabinoids are harmful, beneficial, or benign to the cardiovascular system. This Special Issue, “Cannabinoids and Contractile Function”, welcomes both original research articles and review articles in the field of cannabinoid signaling with an emphasis on, but not limited to, cannabinoid receptor signaling pathways in cardiac and vascular muscle, cannabinoid-mediated cardiovascular dysfunction, and potential cannabinoid receptor-mediated therapeutic targets in cardiovascular disease.

Prof. Dr. Lori A. Walker
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • cannabinoids
  • endocannabinoids
  • cardiac muscle
  • vascular muscle
  • contractility

Published Papers

There is no accepted submissions to this special issue at this moment.
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