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Special Issue "Cardiometabolic Risk: From Omic Technologies to Therapeutic Perspective"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".

Deadline for manuscript submissions: 31 October 2021.

Special Issue Editors

Dr. Laura Sabatino
E-Mail Website
Guest Editor
Institute of Clinical Physiology CNR, Pisa, Italy
Interests: molecular and cellular biology; cell signaling; cardiovascular disease
Dr. Melania Gaggini
E-Mail Website
Guest Editor
Institute of Clinical Physiology CNR, Pisa, Italy
Interests: cardiometabolic disease; biomarkers; lipidomic and metabolic technics

Special Issue Information

Dear Colleagues,

A multifaceted approach and multidisciplinary skills are necessary to face the growing epidemic of obesity and cardiometabolic disease. Many biomarkers associated with different pathophysiological pathways related to obesity and cardiometabolic abnormalities have been identified over the past decades. Nowadays, there is also a growing understanding of omic technologies (e.g. genomics, proteomics, metabolomics, and lipidomics) associated with cardiometabolic alterations. Thus, an effective strategy will likely include precision medicine with the identification of omic-related biomarkers to personalize interventions and improve risk prediction in this setting, taking into account the different relative weighting of cardiometabolic risk factors in the two sexes.

Accordingly, the aim of this special issue is to collect contributions ranging from molecular basis to clinical applications concerning the cardiometabolic risk and disease. Subtopics may include but not limited to the following issues:

  • pathophysiology of cardiometabolic abnormalities
  • genetic determinants in the cardiometabolic risk prediction
  • proteomic, metabolomic, lipidomic pathways involved in cardiometabolic risk and disease
  • assessment of biochemical and molecular biomarkers related to cardiometabolic risk and prevention
  • traditional versus personalized therapeutical approaches targeting cardiometabolic risk and disease
  • gender differences in pathophysiology and therapeutic response in the cardiometabolic setting

Dr. Cristina Vassalle
Dr. Laura Sabatino
Dr. Melania Gaggini
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • obesity
  • multidisciplinary approaches
  • cardiometabolic risk and disease
  • biomarkers
  • omics
  • therapeutic strategies
  • personalized therapy
  • gender-related differences

Published Papers

This special issue is now open for submission.
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