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Special Issue "Dementia and Cell Theraputic Strategies"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".

Deadline for manuscript submissions: 30 June 2021.

Special Issue Editors

Prof. Dr. Kazuyuki Takata
E-Mail Website
Guest Editor
Division of Integrated Pharmaceutical Sciences, Kyoto Pharmaceutical University, Kyoto, Japan
Interests: aging; neurodegenerative diseases; brain immunity; microglia; stem cells; hematopoietic stem cells; regenerative medicine; pharmacological modification
Dr. Daijiro Yanagisawa
E-Mail Website
Guest Editor
Molecular Neuroscience Research Center, Shiga University of Medical Science, Shiga, Japan
Interests: Alzheimer’s disease; tauopathy; molecular imaging; protein aggregation; neurodegeneration; biomarker; disease-modifying therapy

Special Issue Information

Dear Colleagues,

It is estimated that 130 million people worldwide will suffer from dementia by 2050. Alzheimer's disease is the most common form of dementia, and there are many brain disorders that lead to the development of dementia (e.g., Lewy body disease), including Parkinson's disease, cerebrovascular disease, Down's syndrome, and Huntington’s disease. Cell therapeutic strategies are an attractive approach to recovering lost brain function. In fact, the improvement of motor function in Parkinson's disease is vigorously promoted by this strategy, and clinical study is now ongoing. Meanwhile, regarding cell therapeutic strategies for recovery of cognitive functions, preclinical studies have been under examination and/or recently launched to establish the proof of concept. The preclinical studies include not only the evaluation of their effectiveness but also the biology of stem cells; development of technologies for production and tracing of therapeutic cells; elucidation of therapeutic mechanism; and application of materials that support survival, function, and safety of therapeutic cells. Contributions to this Special Issue will provide new insights into the possibility of the development of cell-based disease-modifying therapy and the understanding of the pathogenesis of dementia.

Prof. Dr. Kazuyuki Takata
Dr. Daijiro Yanagisawa
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Alzheimer’s disease
  • amyloid-β
  • tau
  • neurodegeneration
  • neuroinflammation
  • neurons
  • glial cells
  • stem cells
  • Parkinson’s disease
  • Down syndrome
  • regeneration

Published Papers

This special issue is now open for submission.
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