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Special Issue "The Pathogenesis and Therapeutic Strategies for Understanding and Treating Diabetic Neuropathy of the Retina"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".

Deadline for manuscript submissions: 31 August 2021.

Special Issue Editor

Prof. Dr. Toshiyuki Oshitari
E-Mail Website
Guest Editor
Department of Ophthalmology, International University of Health and Welfare School of Medicine, 4-3 Kozunomori, Narita 286-8686, Chiba, Japan
Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Inohana 1-8-1, Chuo-ku, Chiba 260-8670, Chiba, Japan
Interests: diabetic retinopathy; neuronal cell death; neurovascular units; axonal degeneration; glial changes; vascular abnormalities; neuroprotection; regeneration; optic coherence tomography; visual function

Special Issue Information

Dear Colleagues,

There is growing evidence that not only vascular abnormalities but also neuronal abnormalities, including retinal neuronal cell death, are associated with the pathogenesis of diabetic retinopathy. Neuronal cell death is an irreversible change and directly leads to vision loss in diabetic patients. In addition, numerous studies have demonstrated that retinal ganglion cell axons and dendrites are degenerated in the early stage of diabetes. The ultimate purpose of the therapies for patients with diabetic retinopathy is to protect their visual function by neuroprotection, axonal protection, and regeneration. However, the precise pathogenesis of diabetic neuropathy in the retina are still unclear. Diabetic retinopathy is a chronic retinal disease, and it is difficult to determine the pathogenesis of the onset and the progression of neuronal degeneration. Thus, some clues to determine the pathogenesis of the development and the progression of diabetic neuropathy in the retina must be obtained from other acute injury models such as ischemia and physical injury models. Therefore, in this Special Issue, we welcome articles from wide areas of neuroscience that are able to provide clues to determine the pathogenesis of diabetic neuropathy in the retina and to apply therapeutic strategies for the neuroprotection and regeneration of the neurons damaged by diabetic retinopathy.

Prof. Dr. Toshiyuki Oshitari
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • diabetic retinopathy
  • neuronal cell death
  • neurovascular units
  • axonal degeneration
  • glial changes
  • vascular abnormalities
  • neuroprotection
  • regeneration
  • optic coherence tomography
  • visual function

Published Papers

This special issue is now open for submission.
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