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Special Issue "Role of Mitochondrial Genetics in Psychiatric Disorders"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Genetics and Genomics".

Deadline for manuscript submissions: 30 June 2022.

Special Issue Editor

Dr. Lourdes Martorell
E-Mail Website
Guest Editor
Research Department, Hospital Universitari Institut Pere Mata, E43206 Reus, Spain
Interests: medicine neuroscience biochemistry; genetics and molecular biology psychology pharmacology; toxicology and pharmaceutics nursing immunology and microbiology agricultural and biological sciences

Special Issue Information

Dear Colleagues,

The human mitochondrial proteome is estimated to have around 1,500 proteins, most of them are under nuclear genome control; however, mitochondrial DNA, a 16,569 kb circular molecule that encodes 37 genes necessary to synthesize 13 essential subunits of the oxidative phosphorylation system has a relevant role in the generation of most of the cell's energy requirements. Maintaining the balance between energy demand and expenditure is extremely important for the proper functioning of the brain, as the brain uses up to 20% of the body's total energy, while it accounts for only 2% of the body's weight. Mitochondrial genomics plays a key role in brain function, and mitochondrial medicine may provide the impetus for personalized treatments for neuropsychiatric disorders whose biological basis remains unclear, and for which effective treatments are still lacking. Recent and previous studies have already linked mitochondrial genetics to neuropsychiatric diseases. In this special issue, we call for papers that shed light on the association between mitochondrial genomics and psychiatric disorders, as well as the outcome of treatments targeting mitochondria. Of particular interest are papers that 1) identify mitochondrial biomarkers, especially genetic ones, associated with psychiatric phenotypes and 2) identify the relationship between mitochondrial genomics and phenotypic characteristics of psychiatric disorders.

Dr. Lourdes Martorell
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • mitochondria
  • mitochondrial DNA
  • mtDNA
  • psychiatric disorders
  • phenotype
  • treatment
  • outcome

Published Papers

This special issue is now open for submission.
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