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Special Issue "The Role of Extracellular Vesicles in Aging and Disease"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: 28 February 2022.

Special Issue Editors

Prof. Dr. Consuelo Borras
E-Mail Website
Guest Editor
Department of Physiology, Faculty of Medicine, University of Valencia, Avenida Blasco Ibañez 15, 46010 Valencia, Spain
Interests: aging; senescence; stem cells; oxidative stress; sex
Special Issues, Collections and Topics in MDPI journals
Dr. Cristina Mas-Bargues
E-Mail Website
Guest Editor
Department of Physiology, Faculty of Medicine, University of Valencia, Avenida Blasco Ibañez 15, 46010 Valencia, Spain
Interests: stem cells; physioxia; oxidative stress; senescence; apoptosis; autophagy; aging
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

As cells accumulate damage over time, they respond by individual cell fate decisions that disrupt tissue homeostasis, thus leading to organ dysfunction and increased morbidity. Extracellular vesicles (EVs) are known to be able to modulate the aging process by restoring the microenvironment and promoting tissue regeneration. Thus, EVs are promising therapeutic tools, especially in the field of aging and diseases.

However, there is still a long way before EVs can be used at the clinic. Standardization of the methodology, reproducibility and data comparison are major outcomes that must be improved in order to achieve EV-based therapeutics. Therefore, in this Special Issue, we encourage scientists to contribute original articles or reviews describing EV sources, collection and purification methods, as well as EV synthetic designs, such as drug delivery carriers.

Since EV bioactive cargo (proteins, miRNA, lipids) is altered depending on the physio-pathological conditions, we are also looking for studies on EVs’ functional effect on target cells and the underlying mechanisms or signaling pathways that are involved in the process. Finally, we will also welcome research on EV applications for expanding health span, as well as EV use as early biomarkers for disease detection.

Prof. Dr. Consuelo Borras
Dr. Cristina Mas-Bargues
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • extracellular vesicles
  • EV-based therapeutics
  • aging
  • disease
  • biomarkers
  • regenerative medicine
  • stem cells

Published Papers

This special issue is now open for submission.
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