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Enzymology of Respiration and Photosynthesis Processes

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: closed (31 December 2021) | Viewed by 2632

Special Issue Editors


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Guest Editor
Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Leninskie Gory, Moscow 119991, Russia
Interests: biochemistry; molecular mechanisms of enzyme action; molecular bioenergetics; membrane proteins; respiratory chains; terminal oxidases; cytochromes
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Leninskie Gory, Moscow 119991, Russia
Interests: biophysics; biochemistry; molecular bioenergetics; mechanisms of enzyme action; membrane proteins; terminal oxidases; cytochrome oxidase; cytochromes; retinal proteins; photosystem 2; proton pump; electrogenic mechanisms of membrane potential generation; reactive oxygen species; fast kinetics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Energy transduction is a key metabolic process in biological systems. Organisms that harvest free energy from light are of major interest for biotechnology. They may serve as prototypes for gadgets that can harvest electric free energy directly from solar illumination. For instance, the pigment–protein complex of Photosystem II is a key component of the most successful solar energy converting machinery on Earth. The study of the proton pump mechanisms of heme–copper oxidases and retinal proteins at the molecular level can clarify the features of the device and the design of artificial membranes and nanosystems that can efficiently convert different forms of energy. The investigation of respiratory chain enzymes is extremely important and promising from a biomedical point of view. In particular, a comparative study of the heme–copper oxidases and the bd-type oxidases may contribute to the development of new generation antibiotics.

We will appreciate new insights into the molecular mechanisms and structure of respiratory chain and light-transducing enzymes and proteins, their physiological roles, assembly pathways, biotechnological applications, and utility as drug targets. Original research articles and up-to-date reviews on these and related topics are welcome in this Special Issue.

Prof. Dr. Vitaliy Borisov
Prof. Dr. Sergey Siletsky
Guest Editors

Manuscript Submission Information

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Keywords

  • enzyme
  • function
  • physiological role
  • inhibition
  • terminal oxidase
  • cytochrome
  • respiratory chain
  • photosystem
  • retinal
  • proton pump

Published Papers (1 paper)

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Research

12 pages, 2141 KiB  
Article
Sodium Energetic Cycle in the Natronophilic Bacterium Thioalkalivibrio versutus
by Maria S. Muntyan, Mikhail B. Viryasov, Dimitry Y. Sorokin and Vladimir P. Skulachev
Int. J. Mol. Sci. 2022, 23(4), 1965; https://0-doi-org.brum.beds.ac.uk/10.3390/ijms23041965 - 10 Feb 2022
Cited by 2 | Viewed by 1668
Abstract
As inhabitants of soda lakes, Thioalkalivibrio versutus are halo- and alkaliphilic bacteria that have previously been shown to respire with the first demonstrated Na+-translocating cytochrome-c oxidase (CO). The enzyme generates a sodium-motive force (Δs) as high as −270 [...] Read more.
As inhabitants of soda lakes, Thioalkalivibrio versutus are halo- and alkaliphilic bacteria that have previously been shown to respire with the first demonstrated Na+-translocating cytochrome-c oxidase (CO). The enzyme generates a sodium-motive force (Δs) as high as −270 mV across the bacterial plasma membrane. However, in these bacteria, operation of the possible Δs consumers has not been proven. We obtained motile cells and used them to study the supposed Na+ energetic cycle in these bacteria. The resulting motility was activated in the presence of the protonophore 2-heptyl-4-hydroxyquinoline N-oxide (HQNO), in line with the same effect on cell respiration, and was fully blocked by amiloride—an inhibitor of Na+-motive flagella. In immotile starving bacteria, ascorbate triggered CO-mediated respiration and motility, both showing the same dependence on sodium concentration. We concluded that, in T. versutus, Na+-translocating CO and Na+-motive flagella operate in the Na+ energetic cycle mode. Our research may shed light on the energetic reason for how these bacteria are confined to a narrow chemocline zone and thrive in the extreme conditions of soda lakes. Full article
(This article belongs to the Special Issue Enzymology of Respiration and Photosynthesis Processes)
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