Special Issue "Epigenetics, Exosomes, and MicroRNAs in Metabolic Disorders"
Deadline for manuscript submissions: 30 November 2021.
Interests: metabolic disorders (particularly type 2 diabetes and obesity); epigenetics; exosomes; microRNAs and tissue crosstalk in the regulation of metabolism
Maintenance of metabolic homeostasis requires the coordinated action of many cell types. This organismal-level communication is mediated by a variety of secreted factors that regulate cellular function to optimize nutrient fluxes. However, environmental influences may induce aberrant epigenetic modifications and disturb tissue crosstalk, leading to decompensations in fuel use that ultimately result in insulin resistance, obesity, and overt disease. Exosomes and other small vesicles released by, amongst other things, the adipose tissue, regulate gene expression in other tissues through microRNA (miRNA) transfer, hence modulating inter-organ crosstalk.
This Special Issue aims to highlight the latest research on the role of epigenetic modifications and exosome-mediated tissue crosstalk in the development of metabolic disorders. The topics that we intend to cover include the following:
- epigenetics and metabolism;
- exosomes and exosomal miRNAs in the regulation of metabolism;
- exosomes and exosomal miRNAs as biomarkers for metabolic disorders; and
- use of exosomes and extracellular vesicles as therapeutic agents and vectors for the treatment of metabolic disorders.
Dr. Marcelina Prrizas
Dr. Carlos Castaño
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- extracellular vesicles
- epigenetic modifications
- tissue crosstalk
- non-alcoholic fatty liver disease