Special Issue "Extracellular Vesicles as a New Source of Liquid Biopsy 2.0"
Deadline for manuscript submissions: 31 January 2022.
Interests: extracellular vesicles; flow cytometry; biomarkers
Special Issues and Collections in MDPI journals
This Special Issue is the continuation of our previous special issue "Extracellular Vesicles as a New Source of Liquid Biopsy".
Within the past decade, extracellular vesicles have progressively emerged as key regulators of organized communities of cells within multicellular organisms in health and disease. Extracellular vesicles have been described as shuttle vectors or signal transducers that can deliver specific biological information even at long distances. Due to their substantial stability, extracellular vesicles circulate through bodily fluids and have been identified in blood, urine, cerebrospinal fluid, saliva, milk, and tears. It is known that extracellular vesicles are a heterogeneous group of lipidic structures ranging from 30 to 50,000 nm in size, generically subclassified as small, if within 100 nm, and medium/large, if above 100–200 nm.
The extracellular vesicle cargo, consisting of genomic DNA, RNAs, miRNAs, proteins, and lipids dynamically reflecting the characteristics of the cells of origin, makes them an attractive source of biological information. For all of these reasons, extracellular vesicles have high potential as dynamic biomarkers of diseases and/or response to therapies. The deep characterization of extracellular vesicle general characteristics and cargoes related to their roles in tumorigenesis, immunity, and vascular biology may present interesting perspectives in the assessment of extracellular vesicles as a reliable liquid biopsy source.
Dr. Paola Lanuti
Dr. Davide Brocco
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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- Apoptotic bodies
- Large oncosomes
- Extracellular vesicles
- Liquid biopsy
- Intercellular communication