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Special Issue "OMICS Studies of Dietary Supplements"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Genetics and Genomics".

Deadline for manuscript submissions: 31 December 2021.

Special Issue Editor

Dr. Lukasz Huminiecki
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Guest Editor
Zakład Biologii Molekularnej/Department of Molecular Biology, Jastrzębiec, ul. Postępu 36A, 05-552 Magdalenka, Poland

Special Issue Information

Dear Colleagues,

Resveratrol, a natural phenol with anti-oxidant properties, is a phytoalexin. The popularity of resveratrol is increasing as an ingredient of dietary supplements because of its health benefits.

As the putative beneficial effects of resveratrol involve changes in gene expression, they can be studied using transcriptomics. In the context of atherosclerosis, a recent review found that differentially expressed genes induced by resveratrol mimicked changes associated with calorie restriction and lifespan extension [1]. In some cases, expression changes were dose-dependent: involving U-shaped curves of hormetic responses. In the context of malignancy, 17 functional genomic studies of resveratrol confirmed its anti-cancer properties [2].

The Editors seek to update our knowledge on the changes in gene expression induced by resveratrol. We welcome dose-escalation studies, time-courses, tests of hormetic responses, and mathematical models. This Special Issue also seeks RNA-seq studies characterizing alternative transcription start sites or alternative splicing, as well as patterns of expression of microRNAs and long non-coding RNAs.

  1. Huminiecki, L.; Atanasov, A.G.; Horbanczuk, J. Etiology of atherosclerosis informs choice of animal models and tissues for initial functional genomic studies of resveratrol. Pharmacol. Res. 2020, 156, 104598. [PubMed]
  2. Huminiecki, L.; Horbanczuk, J. The functional genomic studies of resveratrol in respect to its anti-cancer effects. Biotechnol. Adv. 2018, 36, 1699–1708. [CrossRef]

Dr. Lukasz Huminiecki
Guest Editor

Manuscript Submission Information

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Published Papers

This special issue is now open for submission.
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